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Rekombinanter GZMB Antikörper

GZMB Reaktivität: Human IHC, ELISA, IF Wirt: Kaninchen Monoclonal 6A1 unconjugated Recombinant Antibody
Produktnummer ABIN7127523
  • Target Alle GZMB Antikörper anzeigen
    GZMB (Granzyme B (GZMB))
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    • 132
    • 52
    • 25
    • 12
    • 4
    • 4
    • 3
    • 1
    Human
    Wirt
    • 81
    • 53
    • 3
    Kaninchen
    Klonalität
    • 80
    • 57
    Monoklonal
    Konjugat
    • 79
    • 13
    • 8
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GZMB Antikörper ist unkonjugiert
    Applikation
    • 70
    • 43
    • 41
    • 37
    • 19
    • 18
    • 16
    • 14
    • 13
    • 10
    • 9
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
    Kreuzreaktivität
    Human
    Aufreinigung
    Affinity-chromatography
    Immunogen
    A synthesized peptide derived from human Granzyme B
    Klon
    6A1
    Isotyp
    IgG
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  • Applikationshinweise
    Recommended dilution: IHC:1:50-1:200, IF:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    GZMB (Granzyme B (GZMB))
    Andere Bezeichnung
    GZMB (GZMB Produkte)
    Hintergrund

    Background: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

    Aliases: Granzyme B (EC 3.4.21.79) (C11) (CTLA-1) (Cathepsin G-like 1) (CTSGL1) (Cytotoxic T-lymphocyte proteinase 2) (Lymphocyte protease) (Fragmentin-2) (Granzyme-2) (Human lymphocyte protein) (HLP) (SECT) (T-cell serine protease 1-3E), GZMB, CGL1 CSPB CTLA1 GRB

    UniProt
    P10144
    Pathways
    Apoptose, Caspase Kaskade in der Apoptose
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