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Rekombinanter HNRNPK Antikörper

HNRNPK Reaktivität: Human WB, IHC, ELISA, IF, IP Wirt: Kaninchen Monoclonal 3G7 unconjugated Recombinant Antibody
Produktnummer ABIN7127548
  • Target Alle HNRNPK Antikörper anzeigen
    HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    • 83
    • 61
    • 56
    • 11
    • 10
    • 10
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 75
    • 9
    Kaninchen
    Klonalität
    • 69
    • 15
    Monoklonal
    Konjugat
    • 49
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HNRNPK Antikörper ist unkonjugiert
    Applikation
    • 62
    • 22
    • 20
    • 14
    • 14
    • 13
    • 12
    • 9
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)
    Kreuzreaktivität
    Human
    Aufreinigung
    Affinity-chromatography
    Immunogen
    A synthesized peptide derived from human HNRNPK
    Klon
    3G7
    Isotyp
    IgG
    Top Product
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  • Applikationshinweise
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200, IP:1:200-1:1000,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
    Andere Bezeichnung
    HNRNPK (HNRNPK Produkte)
    Synonyme
    CSBP antikoerper, HNRPK antikoerper, TUNP antikoerper, Csbp antikoerper, Hnrpk antikoerper, hnrpk antikoerper, MGC75642 antikoerper, wu:fb37h02 antikoerper, wu:fi34c04 antikoerper, zgc:66162 antikoerper, KBBP antikoerper, NOVA antikoerper, heterogeneous nuclear ribonucleoprotein K antikoerper, heterogeneous nuclear ribonucleoprotein K S homeolog antikoerper, heterogeneous nuclear ribonucleoprotein k antikoerper, HNRNPK antikoerper, Hnrnpk antikoerper, hnrnpk.S antikoerper, hnrnpk antikoerper, LOC5565718 antikoerper, CpipJ_CPIJ000130 antikoerper, NGK_p0004 antikoerper
    Hintergrund

    Background: One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction (By similarity). As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest.

    Aliases: Heterogeneous nuclear ribonucleoprotein K, hnRNP K, Transformation up-regulated nuclear protein, TUNP, HNRNPK, HNRPK

    UniProt
    P61978
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