Rekombinanter HSPD1 Antikörper

Produktnummer ABIN7127551

Produktdetails anti-HSPD1 Antikörper

Target: HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser HSPD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Kreuzreaktivität: Human, Maus

Aufreinigung: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Hsp60

Klon: 3D8

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IP:1:200-1:1000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu HSPD1

Target: HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))

Andere Bezeichnung: HSPD1 (HSPD1 Produkte)

Synonyme: CPN60 antikoerper, GROEL antikoerper, HLD4 antikoerper, HSP-60 antikoerper, HSP60 antikoerper, HSP65 antikoerper, HuCHA60 antikoerper, SPG13 antikoerper, chaperonin antikoerper, cpn60 antikoerper, groel antikoerper, hld4 antikoerper, hsp60 antikoerper, hsp65 antikoerper, spg13 antikoerper, 60kDa antikoerper, Hsp60 antikoerper, 12 antikoerper, BP5 antikoerper, CG12101 antikoerper, Cpn60 antikoerper, Dmel\\CG12101 antikoerper, Dmhsp60 antikoerper, G62 antikoerper, HSP60A antikoerper, Hsp60A antikoerper, IEF16 antikoerper, Mmp-P1 antikoerper, SSP 7506 antikoerper, d-hsp60 antikoerper, hsp60A antikoerper, l(1)10Ac antikoerper, l(1)BP5 antikoerper, l(1)G8 antikoerper, l(1)HM21 antikoerper, l(1)L12 antikoerper, l(1)dp025 antikoerper, cb863 antikoerper, fa04a05 antikoerper, fb22d10 antikoerper, fi27b05 antikoerper, id:ibd2197 antikoerper, sb:cb144 antikoerper, wu:fa04a05 antikoerper, wu:fb22d10 antikoerper, wu:fi04a12 antikoerper, wu:fi27b05 antikoerper, MIF4 antikoerper, MNA2 antikoerper, mopA antikoerper, groL antikoerper, crpA antikoerper, Hspd1-30p antikoerper, heat shock protein family D (Hsp60) member 1 antikoerper, heat shock protein family D (Hsp60) member 1 S homeolog antikoerper, 60 kDa heat shock protein, mitochondrial antikoerper, heat shock protein 1 (chaperonin) antikoerper, Heat shock protein 60A antikoerper, heat shock 60 protein 1 antikoerper, chaperone ATPase HSP60 antikoerper, molecular chaperone GroEL antikoerper, thermosome subunit antikoerper, chaperonin GroEL antikoerper, mitochondrial chaperonin antikoerper, heat shock protein family D member 1 antikoerper, HSPD1 antikoerper, hspd1.S antikoerper, hspd1 antikoerper, LOC100414401 antikoerper, Hspd1 antikoerper, Hsp60A antikoerper, HSP60 antikoerper, groEL antikoerper, MMP_RS07785 antikoerper, groEl antikoerper, LOC100136430 antikoerper

Hintergrund:

Background: Chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp10, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix (PubMed:1346131, PubMed:11422376). The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10. This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components. Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein (Probable).

Aliases: 60 kDa heat shock protein, mitochondrial (EC 3.6.4.9) (60 kDa chaperonin) (Chaperonin 60) (CPN60) (Heat shock protein 60) (HSP-60) (Hsp60) (HuCHA60) (Mitochondrial matrix protein P1) (P60 lymphocyte protein), HSPD1, HSP60

UniProt: P10809

Pathways: Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity