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Rekombinanter ILK Antikörper

ILK Reaktivität: Human WB, ELISA, IP, IF Wirt: Kaninchen Monoclonal 6A5 unconjugated Recombinant Antibody
Produktnummer ABIN7127572
  • Target Alle ILK Antikörper anzeigen
    ILK (Integrin-Linked Kinase (ILK))
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    • 108
    • 60
    • 54
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 116
    • 6
    • 1
    Kaninchen
    Klonalität
    • 116
    • 7
    Monoklonal
    Konjugat
    • 62
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser ILK Antikörper ist unkonjugiert
    Applikation
    • 90
    • 46
    • 40
    • 39
    • 24
    • 20
    • 9
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)
    Kreuzreaktivität
    Human, Maus
    Aufreinigung
    Affinity-chromatography
    Immunogen
    A synthesized peptide derived from human ILK
    Klon
    6A5
    Isotyp
    IgG
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  • Applikationshinweise
    Recommended dilution: WB:1:500-1:5000, IF:1:20-1:200, IP:1:200-1:1000,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    ILK (Integrin-Linked Kinase (ILK))
    Andere Bezeichnung
    ILK (ILK Produkte)
    Hintergrund

    Background: Receptor-proximal protein kinase regulating integrin-mediated signal transduction (PubMed:8538749, PubMed:9736715). May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B (PubMed:8538749, PubMed:9736715).

    Aliases: Integrin-linked protein kinase (EC 2.7.11.1) (59 kDa serine/threonine-protein kinase) (ILK-1) (ILK-2) (p59ILK), ILK, ILK1 ILK2

    UniProt
    Q13418
    Pathways
    Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
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