Rekombinanter Lamin A/C Antikörper
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- Target Alle Lamin A/C (LMNA) Antikörper anzeigen
- Lamin A/C (LMNA)
- Antikörpertyp
- Recombinant Antibody
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser Lamin A/C Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)
- Kreuzreaktivität
- Human
- Aufreinigung
- Affinity-chromatography
- Immunogen
- A synthesized peptide derived from human LMNA
- Klon
- 4H7
- Isotyp
- IgG
- Top Product
- Discover our top product LMNA Primärantikörper
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anti-Lamin A/C (LMNA) (AA 403-572) antibody
LMNA Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Lamin A/C (LMNA) antibodyKO Validated LMNA Reaktivität: Human WB, IF, IP, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Lamin A/C (LMNA) (pSer392) antibodyLMNA Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Lamin A/C (LMNA) antibodyKO Validated LMNA Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Monoclonal unconjugated
anti-Lamin A/C (LMNA) antibodyLMNA Reaktivität: Human WB, IHC, ELISA Wirt: Maus Monoclonal 4E7 unconjugated
anti-Lamin A/C (LMNA) (AA 481-646) antibodyLMNA Reaktivität: Human, Maus, Ratte WB, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Lamin A/C (LMNA) (AA 455-469) antibodyLMNA Reaktivität: Human, Maus, Ratte WB, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Lamin A/C (LMNA) antibodyLMNA Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund WB, IHC, ICC, FACS, IHC (fro) Wirt: Maus Monoclonal 133A2 unconjugated
anti-Lamin A/C (LMNA) (C-Term) antibodyLMNA Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Hund, Affe, Pferd, Kaninchen, Hamster, Huhn, Schaf, Meerschweinchen, Avian, Cat, Esel, Ziege WB Wirt: Ziege Polyclonal unconjugated
anti-Lamin A/C (LMNA) (AA 1-664) antibodyLMNA Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
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- Applikationshinweise
- Recommended dilution: IHC:1:50-1:200, IF:1:20-1:200, IP:1:200-1:1000,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- Lamin A/C (LMNA)
- Andere Bezeichnung
- LMNA (LMNA Produkte)
- Hintergrund
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Background: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation (PubMed:10080180, PubMed:22431096, PubMed:10814726, PubMed:11799477, PubMed:18551513). Required for osteoblastogenesis and bone formation (PubMed:12075506, PubMed:15317753, PubMed:18611980). Also prevents fat infiltration of muscle and bone marrow, helping to maintain the volume and strength of skeletal muscle and bone (PubMed:10587585). Required for cardiac homeostasis (PubMed:10580070, PubMed:12927431, PubMed:18611980, PubMed:23666920).
Aliases: Prelamin-A/C, Lamin-A/C, 70 kDa lamin, Renal carcinoma antigen NY-REN-32, LMNA, LMN1
- UniProt
- P02545
- Pathways
- Apoptose, Caspase Kaskade in der Apoptose, ER-Nucleus Signaling, Protein targeting to Nucleus
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