Rekombinanter Menin Antikörper
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- Target Alle Menin (MEN1) Antikörper anzeigen
- Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
- Antikörpertyp
- Recombinant Antibody
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser Menin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- Affinity-chromatography
- Immunogen
- A synthesized peptide derived from human Menin
- Klon
- 8G11
- Isotyp
- IgG
- Top Product
- Discover our top product MEN1 Primärantikörper
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- Applikationshinweise
- Recommended dilution: WB:1:500-1:5000,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
- Andere Bezeichnung
- MEN1 (MEN1 Produkte)
- Synonyme
- MEAI antikoerper, SCG2 antikoerper, menin antikoerper, meai antikoerper, scg2 antikoerper, AW045611 antikoerper, menin 1 antikoerper, menin 1 L homeolog antikoerper, multiple endocrine neoplasia I antikoerper, multiple endocrine neoplasia 1 antikoerper, MEN1 antikoerper, men1 antikoerper, men1.L antikoerper, Men1 antikoerper
- Hintergrund
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Background: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair.
Aliases: Menin, MEN1, SCG2
- UniProt
- O00255
- Pathways
- Chromatin Binding, Positive Regulation of Endopeptidase Activity
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