Rekombinanter PABPN1 Antikörper
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- Target Alle PABPN1 Antikörper anzeigen
- PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))
- Antikörpertyp
- Recombinant Antibody
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser PABPN1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Kreuzreaktivität
- Human
- Aufreinigung
- Affinity-chromatography
- Immunogen
- A synthesized peptide derived from human PABPN1
- Klon
- 6C3
- Isotyp
- IgG
- Top Product
- Discover our top product PABPN1 Primärantikörper
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anti-Poly A Binding Protein Nuclear 1 (PABPN1) antibody
PABPN1 Reaktivität: Human, Maus, Ratte IF, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Poly A Binding Protein Nuclear 1 (PABPN1) (N-Term) antibodyPABPN1 Reaktivität: Human, Maus, Hund, Ratte, Kaninchen, Rind (Kuh), Meerschweinchen WB, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Poly A Binding Protein Nuclear 1 (PABPN1) antibodyPABPN1 Reaktivität: Human WB, IF, ICC, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Poly A Binding Protein Nuclear 1 (PABPN1) (AA 1-100) antibodyPABPN1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Poly A Binding Protein Nuclear 1 (PABPN1) (N-Term) antibodyPABPN1 Reaktivität: Human, Hund, Ratte, Kaninchen, Rind (Kuh), Meerschweinchen, Schwein, Affe WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Poly A Binding Protein Nuclear 1 (PABPN1) (AA 270-298), (C-Term) antibodyPABPN1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB36573 unconjugated
anti-Poly A Binding Protein Nuclear 1 (PABPN1) (C-Term) antibodyPABPN1 Reaktivität: Human, Maus WB, ELISA, IF, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200, FC:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))
- Andere Bezeichnung
- PABPN1 (PABPN1 Produkte)
- Hintergrund
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Background: Involved in the 3'-end formation of mRNA precursors (pre-mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product (By similarity). Stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and controls also the poly(A) tail length (By similarity). Increases the affinity of poly(A) polymerase for RNA (By similarity). Is also present at various stages of mRNA metabolism including nucleocytoplasmic trafficking and nonsense-mediated decay (NMD) of mRNA. Cooperates with SKIP to synergistically activate E-box-mediated transcription through MYOD1 and may regulate the expression of muscle-specific genes (PubMed:11371506). Binds to poly(A) and to poly(G) with high affinity (By similarity). May protect the poly(A) tail from degradation (By similarity).
Aliases: Polyadenylate-binding protein 2 (PABP-2) (Poly(A)-binding protein 2) (Nuclear poly(A)-binding protein 1) (Poly(A)-binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1), PABPN1, PAB2 PABP2
- UniProt
- Q86U42
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