Rekombinanter ERN1 Antikörper (pSer724)
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- Target Alle ERN1 Antikörper anzeigen
- ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))
- Antikörpertyp
- Recombinant Antibody
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Bindungsspezifität
- pSer724
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser ERN1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Aufreinigung
- Affinity-chromatography
- Immunogen
- A synthesized peptide derived from human Phospho-ERN1 (S724)
- Klon
- 1F12
- Isotyp
- IgG
- Top Product
- Discover our top product ERN1 Primärantikörper
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anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 401-500) antibody
ERN1 Reaktivität: Human WB, ELISA, IF, PLA Wirt: Maus Monoclonal 8D12 unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 282-433) antibodyERN1 Reaktivität: Human WB, ELISA, IHC Wirt: Maus Monoclonal 9F2 unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 401-500) antibodyERN1 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 3D1 unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (pSer726) antibodyERN1 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IF (p), IF (cc), ICC, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 252-260) antibodyERN1 Reaktivität: Human, Maus, Ratte, Schwein WB, ELISA, FACS, IF (p), IF (cc), ICC, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (Internal Region) antibodyVerified ERN1 Reaktivität: Human WB, ELISA, FACS Wirt: Ziege Polyclonal unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (C-Term) antibodyERN1 Reaktivität: Human, Maus, Ratte WB, IF, EIA Wirt: Kaninchen Polyclonal unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 493-561) antibodyERN1 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (AA 828-857), (C-Term) antibodyERN1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB16565 unconjugated
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- Applikationshinweise
- Recommended dilution: WB:1:500-1:5000, IF:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))
- Andere Bezeichnung
- ERN1 (ERN1 Produkte)
- Hintergrund
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Background: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation (PubMed:9637683, PubMed:11175748, PubMed:12637535). The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis (PubMed:24508390).
Aliases: Serine/threonine-protein kinase/endoribonuclease IRE1, Endoplasmic reticulum-to-nucleus signaling 1, hIRE1p, Ire1-alpha, IRE1a, Serine/threonine-protein kinase, Endoribonuclease, ERN1
- UniProt
- O75460
- Pathways
- ER-Nucleus Signaling, Unfolded Protein Response
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