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Rekombinanter LAT Antikörper (pTyr191)

Name: Rekombinanter LAT Antikörper (pTyr191)
Brand: antibodies-online
SKU: ABIN7127705
Price: 385 EUR
Availability: InStock

LAT Reaktivität: Human WB, ELISA, IHC, IP, IF Wirt: Kaninchen Monoclonal 2E4 unconjugated Recombinant Antibody

Immunoprecipitating Phospho-LAT in A549 whole cell lysate Lane 1: Rabbit control IgG(1μg)instead of ABIN7127705 in A549 whole cell lysate. (Rekombinanter LAT Antikörper (pTyr191))

Western Blot Positive WB detected in:Jurkat whole cell lysate, Hela whole cell lysate, HepG2 whole cell lysate(treated with EGF or Pervanadate) All lanes: Phospho-LAT antibody at 2. (Rekombinanter LAT Antikörper (pTyr191))

IHC image of ABIN7127705 diluted at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. (Rekombinanter LAT Antikörper (pTyr191))

IHC

IHC image of ABIN7127705 diluted at 1:100 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. (Rekombinanter LAT Antikörper (pTyr191))

IHC

Immunofluorescence staining of Hela cells with ABIN7127705 at 1:100,counter-stained with DAPI. (Rekombinanter LAT Antikörper (pTyr191))

5 Abbildungen

Produktnummer ABIN7127705

Datenblatt (PDF)

Target Alle LAT Antikörper anzeigen

LAT (Linker For Activation of T Cells (LAT))

Antikörpertyp

Recombinant Antibody
Bindungsspezifität
21

19

15

8

8

7

7

7

4

4

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pTyr191
Reaktivität
143

61

43

1
Human
Wirt
125

19

2

1
Kaninchen
Passende Sekundärantikörper
Klonalität
129

18
Monoklonal
Konjugat
70

7

6

6

4

4

4

4

4

3

3

3

3

3

3

3

3

3

3

3

3

2
Dieser LAT Antikörper ist unkonjugiert
Applikation
77

45

39

39

16

12

9

9

6

4

2

2

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Kreuzreaktivität

Human

Aufreinigung

Affinity-chromatography

Immunogen

A synthesized peptide derived from human Phospho-LAT (Y191)

Klon

2E4

Isotyp

IgG

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Applikationshinweise

Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200, IP:1:200-1:1000,

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C,-80 °C

Informationen zur Lagerung

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target

LAT (Linker For Activation of T Cells (LAT))

Andere Bezeichnung

LAT (LAT Produkte)

Synonyme

LAT antikoerper, lat antikoerper, LAT1 antikoerper, pp36 antikoerper, linker for activation of T-cells antikoerper, linker for activation of T cells antikoerper, LAT antikoerper, lat antikoerper, Lat antikoerper

Hintergrund

Background: Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.
Aliases: Linker for activation of T-cells family member 1, 36 kDa phospho-tyrosine adapter protein, pp36, p36-38, LAT

UniProt

O43561

Pathways

T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung