Rekombinanter NRF2 Antikörper (pSer40)

Produktnummer ABIN7127720

Produktdetails anti-NRF2 Antikörper

Target: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Antikörpertyp: Recombinant Antibody

Bindungsspezifität: pSer40

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser NRF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Phospho-NFE2L2 (S40)

Klon: 2E6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu NRF2

Target: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Andere Bezeichnung: NFE2L2 (NFE2L2 Produkte)

Synonyme: Nrf2 antikoerper, nfe2l2 antikoerper, wu:fc15g09 antikoerper, wu:fj67e03 antikoerper, NF-E2R2 antikoerper, NRF2 antikoerper, AI194320 antikoerper, nuclear factor, erythroid 2-like 2a antikoerper, nuclear factor, erythroid 2 like 2 S homeolog antikoerper, nuclear factor, erythroid 2 like 2 antikoerper, nuclear factor, erythroid derived 2, like 2 antikoerper, nuclear factor, erythroid 2-like 2 antikoerper, nfe2l2a antikoerper, nfe2l2.S antikoerper, NFE2L2 antikoerper, Nfe2l2 antikoerper

Hintergrund:

Background: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.

Aliases: Nuclear factor erythroid 2-related factor 2, NF-E2-related factor 2, NFE2-related factor 2, HEBP1, Nuclear factor, erythroid derived 2, like 2, NFE2L2, NRF2

UniProt: Q16236

Pathways: ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling