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Rekombinanter PKM Antikörper

PKM Reaktivität: Human ELISA, WB, IHC, IF, IP, FACS Wirt: Kaninchen Monoclonal 7B2 unconjugated Recombinant Antibody
Produktnummer ABIN7127769
  • Target Alle PKM Antikörper anzeigen
    PKM (Pyruvate Kinase M1/2 (PKM))
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    • 38
    • 11
    • 5
    • 3
    Human
    Wirt
    • 35
    • 5
    • 3
    Kaninchen
    Klonalität
    • 38
    • 5
    Monoklonal
    Konjugat
    • 25
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PKM Antikörper ist unkonjugiert
    Applikation
    • 28
    • 22
    • 13
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)
    Kreuzreaktivität
    Human, Maus
    Aufreinigung
    Affinity-chromatography
    Immunogen
    A synthesized peptide derived from human PKM2
    Klon
    7B2
    Isotyp
    IgG
    Top Product
    Discover our top product PKM Primärantikörper
  • Applikationshinweise
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200, FC:1:20-1:200, IP:1:200-1:1000,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    PKM (Pyruvate Kinase M1/2 (PKM))
    Andere Bezeichnung
    PKM (PKM Produkte)
    Hintergrund

    Background: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.

    Aliases: Pyruvate kinase PKM (EC 2.7.1.40) (Cytosolic thyroid hormone-binding protein) (CTHBP) (Opa-interacting protein 3) (OIP-3) (Pyruvate kinase 2/3) (Pyruvate kinase muscle isozyme) (Thyroid hormone-binding protein 1) (THBP1) (Tumor M2-PK) (p58), PKM, OIP3 PK2 PK3 PKM2

    UniProt
    P14618
    Pathways
    Warburg Effekt
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