Rekombinanter PKM Antikörper
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- Target Alle PKM Antikörper anzeigen
- PKM (Pyruvate Kinase M1/2 (PKM))
- Antikörpertyp
- Recombinant Antibody
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser PKM Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)
- Kreuzreaktivität
- Human, Maus
- Aufreinigung
- Affinity-chromatography
- Immunogen
- A synthesized peptide derived from human PKM2
- Klon
- 7B2
- Isotyp
- IgG
- Top Product
- Discover our top product PKM Primärantikörper
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anti-Pyruvate Kinase M1/2 (PKM) (AA 2-531) antibody
PKM Reaktivität: Human ELISA, WB, IHC, IF, IP, FACS Wirt: Maus Monoclonal 6C3C7 unconjugated
anti-Pyruvate Kinase M1/2 (PKM) (AA 11-221) antibodyPKM Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Pyruvate Kinase M1/2 (PKM) (AA 185-461) antibodyPKM Reaktivität: Human ELISA, WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Pyruvate Kinase M1/2 (PKM) (AA 11-221) antibodyPKM Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Pyruvate Kinase M1/2 (PKM) (Internal Region) antibodyPKM Reaktivität: Human, Maus, Ratte ELISA, WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Pyruvate Kinase M1/2 (PKM) (AA 2-192) antibodyPKM Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Pyruvate Kinase M1/2 (PKM) (pSer37) antibodyPKM Reaktivität: Human ELISA, WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Pyruvate Kinase M1/2 (PKM) antibodyPKM Reaktivität: Human, Maus, Ratte ELISA, WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Pyruvate Kinase M1/2 (PKM) (pSer37) antibodyPKM Reaktivität: Human, Maus, Ratte ELISA, WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Pyruvate Kinase M1/2 (PKM) (pTyr105) antibodyPKM Reaktivität: Human, Maus ELISA, WB, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200, FC:1:20-1:200, IP:1:200-1:1000,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- PKM (Pyruvate Kinase M1/2 (PKM))
- Andere Bezeichnung
- PKM (PKM Produkte)
- Hintergrund
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Background: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
Aliases: Pyruvate kinase PKM (EC 2.7.1.40) (Cytosolic thyroid hormone-binding protein) (CTHBP) (Opa-interacting protein 3) (OIP-3) (Pyruvate kinase 2/3) (Pyruvate kinase muscle isozyme) (Thyroid hormone-binding protein 1) (THBP1) (Tumor M2-PK) (p58), PKM, OIP3 PK2 PK3 PKM2
- UniProt
- P14618
- Pathways
- Warburg Effekt
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