Rekombinanter PTBP1 Antikörper
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- Target Alle PTBP1 Antikörper anzeigen
- PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))
- Antikörpertyp
- Recombinant Antibody
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser PTBP1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- Affinity-chromatography
- Immunogen
- A synthesized peptide derived from human PTBP1
- Klon
- 8A1
- Isotyp
- IgG
- Top Product
- Discover our top product PTBP1 Primärantikörper
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anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 45-144) antibody
PTBP1 Reaktivität: Human WB, ELISA, IF, IHC (p), IP Wirt: Maus Monoclonal 3H8 unconjugated
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 1-100) antibodyPTBP1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (N-Term) antibodyVerified PTBP1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Ziege Polyclonal unconjugated
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 1-290) antibodyPTBP1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) antibodyPTBP1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Monoclonal unconjugated
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 26-55), (N-Term) antibodyPTBP1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB40967 unconjugated
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 1-557) antibodyPTBP1 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (N-Term) antibodyPTBP1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 45-145) antibodyPTBP1 Reaktivität: Human WB, IHC, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 3H8 unconjugated
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) antibodyPTBP1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))
- Andere Bezeichnung
- PTBP1 (PTBP1 Produkte)
- Hintergrund
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Background: Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10 (PubMed:15009664). In case of infection by picornaviruses, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:21518806).
Aliases: Polypyrimidine tract-binding protein 1 (PTB) (57 kDa RNA-binding protein PPTB-1) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I), PTBP1, PTB
- UniProt
- P26599
- Pathways
- Regulation of Muscle Cell Differentiation
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