Rekombinanter RPE65 Antikörper

Produktnummer ABIN7127798

Produktdetails anti-RPE65 Antikörper

Target: RPE65 (Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser RPE65 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: Affinity-chromatography

Immunogen: A synthesized peptide derived from human RPE65

Klon: 7B10

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu RPE65

Target: RPE65 (Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))

Andere Bezeichnung: RPE65 (RPE65 Produkte)

Synonyme: LCA2 antikoerper, RP20 antikoerper, mRPE65 antikoerper, rd12 antikoerper, sRPE65 antikoerper, 65kDa antikoerper, A930029L06Rik antikoerper, Mord1 antikoerper, DRPE65 antikoerper, RPE65 antikoerper, anon-WO0148162.1 antikoerper, anon-WO0148163.1 antikoerper, beta-diox antikoerper, DmelCG9347 antikoerper, CG9347 antikoerper, MGC52887 antikoerper, MGC154296 antikoerper, MGC85437 antikoerper, rpe65 antikoerper, RPE56c antikoerper, si:ch211-198n5.12 antikoerper, 13cIMH antikoerper, RPE56b antikoerper, rpepb antikoerper, si:ch211-198n5.5 antikoerper, wu:fc74c09 antikoerper, zgc:110538 antikoerper, RPE56a antikoerper, rpepa antikoerper, zgc:73213 antikoerper, RPE65, retinoid isomerohydrolase antikoerper, retinal pigment epithelium 65 antikoerper, neither inactivation nor afterpotential B antikoerper, retinal pigment epithelium-specific protein 65kDa S homeolog antikoerper, retinal pigment epithelium-specific protein 65kDa L homeolog antikoerper, RPE65 homolog antikoerper, retinal pigment epithelium-specific protein 65kDa antikoerper, retinal pigment epithelium-specific protein 65c antikoerper, retinal pigment epithelium-specific protein 65b antikoerper, retinal pigment epithelium-specific protein 65a antikoerper, RPE65 antikoerper, Rpe65 antikoerper, ninaB antikoerper, rpe65.S antikoerper, rpe65.L antikoerper, rpe65 antikoerper, rpe65c antikoerper, rpe65b antikoerper, rpe65a antikoerper

Hintergrund:

Background: Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT. The enzymatic activity is linearly dependent of the expression levels and membrane association.

Aliases: Retinoid isomerohydrolase (EC 3.1.1.64) (All-trans-retinyl-palmitate hydrolase) (Meso-zeaxanthin isomerase) (EC 5.3.3.-) (Retinal pigment epithelium-specific 65 kDa protein) (Retinol isomerase), RPE65

UniProt: Q16518