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Rekombinanter RPE65 Antikörper

RPE65 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Monoclonal 7B10 unconjugated Recombinant Antibody
Produktnummer ABIN7127798
  • Target Alle RPE65 Antikörper anzeigen
    RPE65 (Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    • 41
    • 31
    • 31
    • 10
    • 2
    • 1
    • 1
    Human
    Wirt
    • 40
    • 7
    • 1
    Kaninchen
    Klonalität
    • 30
    • 18
    Monoklonal
    Konjugat
    • 17
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RPE65 Antikörper ist unkonjugiert
    Applikation
    • 36
    • 14
    • 13
    • 9
    • 8
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    Affinity-chromatography
    Immunogen
    A synthesized peptide derived from human RPE65
    Klon
    7B10
    Isotyp
    IgG
    Top Product
    Discover our top product RPE65 Primärantikörper
  • Applikationshinweise
    Recommended dilution: IHC:1:50-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    RPE65 (Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))
    Andere Bezeichnung
    RPE65 (RPE65 Produkte)
    Hintergrund

    Background: Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT. The enzymatic activity is linearly dependent of the expression levels and membrane association.

    Aliases: Retinoid isomerohydrolase (EC 3.1.1.64) (All-trans-retinyl-palmitate hydrolase) (Meso-zeaxanthin isomerase) (EC 5.3.3.-) (Retinal pigment epithelium-specific 65 kDa protein) (Retinol isomerase), RPE65

    UniProt
    Q16518
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