Rekombinanter SKP2 Antikörper
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- Target Alle SKP2 Antikörper anzeigen
- SKP2 (S-Phase Kinase-Associated Protein 2 (SKP2))
- Antikörpertyp
- Recombinant Antibody
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser SKP2 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Aufreinigung
- Affinity-chromatography
- Immunogen
- A synthesized peptide derived from human SKP2
- Klon
- 6D4
- Isotyp
- IgG
- Top Product
- Discover our top product SKP2 Primärantikörper
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anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 351-424) antibody
SKP2 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (C-Term) antibodySKP2 Reaktivität: Human, Maus WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 1-100) antibodySKP2 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) antibodySKP2 Reaktivität: Human WB, IHC Wirt: Kaninchen Monoclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 43-397) antibodySKP2 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 1-424) antibodySKP2 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) antibodySKP2 Reaktivität: Human ELISA, IF, FACS Wirt: Kaninchen Monoclonal 3C11 unconjugated Recombinant Antibody
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 156-185) antibodySKP2 Reaktivität: Human WB, FACS Wirt: Kaninchen Polyclonal RB19860 unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 1-130) antibodySKP2 Reaktivität: Human ELISA Wirt: Maus Monoclonal 6G9D10 unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 1-424) antibodySKP2 Reaktivität: Human WB, PLA Wirt: Maus Polyclonal unconjugated
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- Applikationshinweise
- Recommended dilution: IHC:1:50-1:200, IF:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- SKP2 (S-Phase Kinase-Associated Protein 2 (SKP2))
- Andere Bezeichnung
- SKP2 (SKP2 Produkte)
- Synonyme
- FBXL1 antikoerper, FBL1 antikoerper, FLB1 antikoerper, p45 antikoerper, RGD1562456 antikoerper, S-phase kinase-associated protein 2 (p45) antikoerper, S-phase kinase associated protein 2 antikoerper, Skp2 antikoerper, SKP2 antikoerper
- Hintergrund
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Background: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. Degradation of CDKN1B/p27kip also requires CKS1. Recognizes target proteins ORC1, CDT1, RBL2, KMT2A/MLL1, CDK9, RAG2, FOXO1, UBP43, and probably MYC, TOB1 and TAL1. Degradation of TAL1 also requires STUB1. Recognizes CDKN1A in association with CCNE1 or CCNE2 and CDK2. Promotes ubiquitination and destruction of CDH1 in a CK1-Dependent Manner, thereby regulating cell migration.
Aliases: S-phase kinase-associated protein 2 (Cyclin-A/CDK2-associated protein p45) (F-box protein Skp2) (F-box/LRR-repeat protein 1) (p45skp2), SKP2, FBXL1
- UniProt
- Q13309
- Pathways
- Mitotic G1-G1/S Phases
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