Rekombinanter TXN Antikörper
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- Target Alle TXN Antikörper anzeigen
- TXN (Thioredoxin (TXN))
- Antikörpertyp
- Recombinant Antibody
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser TXN Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Kreuzreaktivität
- Human, Ratte
- Aufreinigung
- Affinity-chromatography
- Immunogen
- A synthesized peptide derived from human TRX1
- Klon
- 3G7
- Isotyp
- IgG
- Top Product
- Discover our top product TXN Primärantikörper
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- Applikationshinweise
- Recommended dilution: WB:1:500-1:5000,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- TXN (Thioredoxin (TXN))
- Andere Bezeichnung
- TXN (TXN Produkte)
- Hintergrund
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Background: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.
Aliases: Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP), TXN, TRDX TRX TRX1
- UniProt
- P10599
- Pathways
- Carbohydrate Homeostasis, Cell RedoxHomeostasis
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