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Rekombinanter NKX2-1 Antikörper

NKX2-1 Reaktivität: Human WB, FACS, IHC, ELISA Wirt: Kaninchen Monoclonal 6C11 unconjugated Recombinant Antibody
Produktnummer ABIN7127859
  • Target Alle NKX2-1 Antikörper anzeigen
    NKX2-1 (NK2 Homeobox 1 (NKX2-1))
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    • 74
    • 37
    • 37
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 45
    • 30
    Kaninchen
    Klonalität
    • 39
    • 36
    Monoklonal
    Konjugat
    • 42
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NKX2-1 Antikörper ist unkonjugiert
    Applikation
    • 37
    • 34
    • 26
    • 24
    • 20
    • 16
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    Affinity-chromatography
    Immunogen
    A synthesized peptide derived from human TTF1
    Klon
    6C11
    Isotyp
    IgG
    Top Product
    Discover our top product NKX2-1 Primärantikörper
  • Applikationshinweise
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, FC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    NKX2-1 (NK2 Homeobox 1 (NKX2-1))
    Andere Bezeichnung
    NKX2-1 (NKX2-1 Produkte)
    Hintergrund

    Background: Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1 (By similarity).

    Aliases: Homeobox protein Nkx-2.1 (Homeobox protein NK-2 homolog A) (Thyroid nuclear factor 1) (Thyroid transcription factor 1) (TTF-1) (Thyroid-specific enhancer-binding protein) (T/EBP), NKX2-1, NKX2A TITF1 TTF1

    UniProt
    P43699
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour
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