ANTXR1 Antikörper
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- Target Alle ANTXR1 Antikörper anzeigen
- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ANTXR1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Antigen affinity purification
- Immunogen
- Fusion protein of Human ANTXR1
- Isotyp
- IgG
- Top Product
- Discover our top product ANTXR1 Primärantikörper
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- Applikationshinweise
- ELISA:1:1000-1:2000, WB:1:200-1:1000,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
- Andere Bezeichnung
- ANTXR1 (ANTXR1 Produkte)
- Synonyme
- ANTXR1 antikoerper, ATR antikoerper, TEM8 antikoerper, 2310008J16Rik antikoerper, 2810405N18Rik antikoerper, Antrx1 antikoerper, Tem8 antikoerper, anthrax toxin receptor 1 antikoerper, ANTXR1 antikoerper, Antxr1 antikoerper
- Hintergrund
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Background: This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.
Aliases: Anthrax toxin receptor 1 antibody, ANTR1_HUMAN antibody, Antxr1 antibody, ATR antibody, Tumor endothelial marker 8 antibody
- UniProt
- Q9H6X2
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