SOCS6 Antikörper

Produktnummer ABIN7131139

Produktdetails anti-SOCS6 Antikörper

Target: SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOCS6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Kreuzreaktivität: Human, Maus

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of Human SOCS6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SOCS6

Target: SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))

Andere Bezeichnung: SOCS6 (SOCS6 Produkte)

Hintergrund:

Background: The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.

Aliases: CIS-4 antibody, CIS4 antibody, Cish4 antibody, Cytokine inducible SH2 protein 4 antibody, Cytokine-inducible SH2 protein 4 antibody, HSPC060 antibody, SOCS-4 antibody, SOCS-6 antibody, SOCS4 antibody, Socs6 antibody, SOCS6_HUMAN antibody, SSI4 antibody, STAI4 antibody, STAT induced STAT inhibitor 4 antibody, STAT4 antibody, STATI4 antibody, Suppressor of cytokine signaling 4 antibody, Suppressor of cytokine signaling 6 antibody

UniProt: O14544

Pathways: JAK-STAT Signalweg, Carbohydrate Homeostasis