TWIST2 Antikörper

Produktnummer ABIN7138153

Produktdetails anti-TWIST2 Antikörper

Target: TWIST2 (Twist Homolog 2 (TWIST2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TWIST2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: Peptide sequence around aa.26~30(P-K-R-F-G) derived from Human Twist2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:1000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TWIST2

Target: TWIST2 (Twist Homolog 2 (TWIST2))

Andere Bezeichnung: TWIST2 (TWIST2 Produkte)

Synonyme: TWIST2 antikoerper, DERMO1 antikoerper, FFDD3 antikoerper, SETLSS antikoerper, bHLHa39 antikoerper, Dermo1 antikoerper, CDERMO-1 antikoerper, twist family bHLH transcription factor 2 antikoerper, twist basic helix-loop-helix transcription factor 2 antikoerper, TWIST2 antikoerper, Twist2 antikoerper

Hintergrund:

Background:

Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism. Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.

Lee M.S., Lowe G., Flanagan S., Kuchler K., Glackin C.A.Bone 27:591-602(2000)

Aliases: bHLHa39 antibody, Class A basic helix-loop-helix protein 39 antibody, Dermis expressed protein 1 antibody, Dermis-expressed protein 1 antibody, DERMO 1 antibody, Dermo-1 antibody, DERMO1 antibody, MGC117334 antibody, Twist 2 antibody, Twist homolog 2 (Drosophila) antibody, Twist homolog 2 antibody, Twist related bHLH protein Dermo1 antibody, Twist related protein 2 antibody, Twist-related protein 2 antibody, Twist2 antibody, TWST2_HUMAN antibody

UniProt: Q8WVJ9

Pathways: Chromatin Binding