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Cofilin Antikörper (pSer3)

CFL1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7138534
  • Target Alle Cofilin (CFL1) Antikörper anzeigen
    Cofilin (CFL1) (Cofilin 1 (CFL1))
    Bindungsspezifität
    • 18
    • 16
    • 16
    • 15
    • 11
    • 8
    • 8
    • 7
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer3
    Reaktivität
    • 131
    • 93
    • 91
    • 5
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 136
    • 9
    • 2
    Kaninchen
    Klonalität
    • 135
    • 11
    Polyklonal
    Konjugat
    • 70
    • 10
    • 10
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Cofilin Antikörper ist unkonjugiert
    Applikation
    • 70
    • 58
    • 42
    • 42
    • 41
    • 41
    • 30
    • 28
    • 17
    • 13
    • 7
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    Immunogen
    Peptide sequence around phosphorylation site of serine 3 (M-A-S(p)-G-V) derived from Human cofilin.
    Isotyp
    IgG
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  • Applikationshinweise
    WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    Cofilin (CFL1) (Cofilin 1 (CFL1))
    Andere Bezeichnung
    CFL1 (CFL1 Produkte)
    Hintergrund

    Background: Controls reversibly actin polymerization and depolymerization in a pH -sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.

    Kobayashi M, et al. (2006) EMBO J 25(4): 713-26.
    Wang Y, et al. (2005) Biol Chem 280(13): 12683-9.
    Smith-Beckerman DM, et al. (2005) Mol Cell Proteomics: 156-68.

    Aliases: 18 kDa phosphoprotein antibody, CFL 1 antibody, CFL antibody, CFL1 antibody, COF1_HUMAN antibody, Cofilin 1 antibody, Cofilin 1 non muscle antibody, Cofilin antibody, Cofilin non muscle isoform antibody, Cofilin-1 antibody, epididymis secretory protein Li 15 antibody, HEL-S-15 antibody, non-muscle isoform antibody, p18 antibody

    UniProt
    P23528
    Pathways
    Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
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