SUFUH Antikörper (pSer342)

Produktnummer ABIN7138564

Produktdetails anti-SUFUH Antikörper

Target: SUFUH (Suppressor of Fused Homolog (SUFUH))

Bindungsspezifität: pSer342

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SUFUH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: Peptide sequence around phosphorylation site of Serine 342 (A-P-S(p)-R-K) derived from Human Sufu.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:1000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SUFUH

Target: SUFUH (Suppressor of Fused Homolog (SUFUH))

Andere Bezeichnung: SUFU (SUFUH Produkte)

Synonyme: CG6054 antikoerper, Dmel\\CG6054 antikoerper, SU(FU) antikoerper, SUFU antikoerper, Su(Fu) antikoerper, SuFu antikoerper, Sufu antikoerper, su(fu) antikoerper, sufu antikoerper, Xsufu antikoerper, sufuh antikoerper, sufuxl antikoerper, PRO1280 antikoerper, SUFUH antikoerper, SUFUXL antikoerper, Su(fu) antikoerper, dre antikoerper, fi39e05 antikoerper, wu:fi39e05 antikoerper, 2810026F04Rik antikoerper, b2b273Clo antikoerper, Suppressor of fused antikoerper, SUFU negative regulator of hedgehog signaling L homeolog antikoerper, SUFU negative regulator of hedgehog signaling antikoerper, suppressor of fused homolog (Drosophila) antikoerper, Su(fu) antikoerper, sufu.L antikoerper, SUFU antikoerper, sufu antikoerper, Sufu antikoerper

Hintergrund:

Background: SUFU encodes a component of the Sonic hedgehog (SHH, MIM 600725)/Patched (PTCH, MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945, BCNS, MIM 109400, and GCPS, MIM 175700)

Zimmern P,et al.(2010) Neurourol Urodyn.29(5):715-8.
Wang C,et al. (2010) Development. 137(12):2001-9.
Rabasseda X.et al.(2010) Drug News Perspect.23(4):273-5.

Aliases: OTTHUMP00000020374 antibody, OTTHUMP00000020377 antibody, OTTHUMP00000020379 antibody, PRO1280 antibody, SU FU antibody, SU(F)U antibody, Su(fu) antibody, SUFU antibody, SUFU negative regulator of hedgehog signaling antibody, SUFU_HUMAN antibody, SUFUH antibody, SUFUXL antibody, Suppressor of Fused antibody, Suppressor of fused homolog (Drosophila) antibody, Suppressor of fused homolog antibody

UniProt: Q9UMX1

Pathways: Hedgehog Signalweg, Tube Formation, Maintenance of Protein Location