HDAC8 Antikörper (pSer39)
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- Target Alle HDAC8 Antikörper anzeigen
- HDAC8 (Histone Deacetylase 8 (HDAC8))
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Bindungsspezifität
- pSer39
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HDAC8 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Immunogen
- Peptide sequence around phosphorylation site of serine 39 (R-A-S(p)-M-V) derived from Human HDAC8.
- Isotyp
- IgG
- Top Product
- Discover our top product HDAC8 Primärantikörper
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- Applikationshinweise
- IHC:1:50-1:100, IF:1:100-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- HDAC8 (Histone Deacetylase 8 (HDAC8))
- Andere Bezeichnung
- HDAC8 (HDAC8 Produkte)
- Synonyme
- HD8 antikoerper, CDLS5 antikoerper, HDACL1 antikoerper, MRXS6 antikoerper, RPD3 antikoerper, WTS antikoerper, 2610007D20Rik antikoerper, RGD1562895 antikoerper, wu:fd19a02 antikoerper, zgc:66196 antikoerper, ATHDA8 antikoerper, HDA8 antikoerper, HISTONE DEACETYLASE 8 antikoerper, T27G7.14 antikoerper, T27G7_14 antikoerper, histone deacetylase 8 antikoerper, histone deacetylase 8 antikoerper, histone deacetylase 8 L homeolog antikoerper, CC1G_05302 antikoerper, hdac8 antikoerper, HDAC8 antikoerper, Hdac8 antikoerper, hdac8.L antikoerper, HDA08 antikoerper
- Hintergrund
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Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC8 gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.
Lee H, et al. (2004) Mol Cell Biol. 24(2): 765-773.Aliases: CDA07 antibody, CDLS5 antibody, HD 8 antibody, HD8 antibody, HDAC 8 antibody, Hdac8 antibody, HDAC8_HUMAN antibody, HDACL 1 antibody, HDACL1 antibody, Histone deacetylase 8 antibody, Histone deacetylase like 1 antibody, MRXS6 antibody, RPD 3 antibody, RPD3 antibody, WTS antibody
- UniProt
- Q9BY41
- Pathways
- Cellular Glucan Metabolic Process
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