Girdin Antikörper (pSer417)

Produktnummer ABIN7138609

Produktdetails anti-Girdin Antikörper

Target: Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))

Bindungsspezifität: pSer417

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Girdin Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Maus

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of Serine 417(L-E-M(p)-A-Q) derived from Human Girdin .

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC:1:50-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Girdin

Target: Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))

Andere Bezeichnung: CCDC88A (CCDC88A Produkte)

Hintergrund:

Background:

girdin IS a ubiquitously expressed actin binding protein that plays an important role in the formation of stress fibers and lamellipodia. Subsequent to phosphorylation by Akt, Girdin accumulates at the leading edge of migrating cells and appears to be crucial for the integrity of the actin cytoskeleton and for cell migration.

Enomoto A., Dev. Cell 9:389-402(2005).
Simpson F., Traffic 6:442-458(2005).
Hillier L.W., Nature 434:724-731(2005).

Aliases: AKT iphosphorylation enhancer antibody, Akt phosphorylation enhancer antibody, APE antibody, Ccdc88a antibody, Coiled coil domain containing 88A antibody, Coiled coil domain containing protein 88A antibody, Coiled-coil domain-containing protein 88A antibody, FLJ10392 antibody, G alpha interacting vesicle associated protein antibody, G alpha-interacting vesicle-associated protein antibody, Galpha interacting vesicle associated protein antibody, Girders of actin filament antibody, Girdin antibody, GIV antibody, GRDN antibody, GRDN_HUMAN antibody, HkRP1 antibody, Hook related protein 1 antibody, Hook-related protein 1 antibody, KIAA1212 antibody

UniProt: Q3V6T2