Splicing Factor 1 Antikörper (pSer82)

Produktnummer ABIN7138709

Produktdetails anti-Splicing Factor 1 Antikörper

Target: Splicing Factor 1 (SF1)

Bindungsspezifität: pSer82

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Splicing Factor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Maus

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of Serine 82(S-P-S(p)-P-E) derived from Human SF1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:1000, IHC:1:50-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Splicing Factor 1

Target: Splicing Factor 1 (SF1)

Andere Bezeichnung: SF1 (SF1 Produkte)

Synonyme: BBP antikoerper, D11S636 antikoerper, MBBP antikoerper, ZCCHC25 antikoerper, ZFM1 antikoerper, ZNF162 antikoerper, BB094781 antikoerper, CW17R antikoerper, MZFM antikoerper, WBP4 antikoerper, Zfp162 antikoerper, CG5836 antikoerper, Dmel\\CG5836 antikoerper, cg5836 antikoerper, dSF1 antikoerper, p70 antikoerper, SF1 antikoerper, sf1 antikoerper, wu:fc09f06 antikoerper, znf162 antikoerper, MWD22.25 antikoerper, MWD22_25 antikoerper, SF-1 antikoerper, splicing factor 1 antikoerper, Splicing factor 1 antikoerper, splicing factor-like protein antikoerper, nuclear receptor subfamily 5 group A member 1 antikoerper, splicing factor 1 S homeolog antikoerper, SF1 antikoerper, Sf1 antikoerper, sf1 antikoerper, AT5G51300 antikoerper, NR5A1 antikoerper, sf1.S antikoerper

Hintergrund:

Background:

Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor.

Susan Y. Park, Development, May 2005, 132: 2415 - 2423.
Dujin Zhou, Mol. Endocrinol., Jul 2000, 14: 986.
Dagmar Wilhelm, Genes & Dev., Jul 2002, 16: 1839.
Philipp Gut,Development, Oct 2005, 132: 4611 - 4619.

Aliases: SF1 antibody, ZFM1 antibody, ZNF162 antibody, Splicing factor 1 antibody, Mammalian branch point-binding protein antibody, BBP antibody, mBBP antibody, Transcription factor ZFM1 antibody, Zinc finger gene in MEN1 locus antibody, Zinc finger protein 162 antibody

UniProt: Q15637

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Maintenance of Protein Location