BAD Antikörper (pSer91, pSer128)
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- Target Alle BAD Antikörper anzeigen
- BAD (BCL2-Associated Agonist of Cell Death (BAD))
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Bindungsspezifität
- pSer91, pSer128
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser BAD Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Immunogen
- Peptide sequence around phosphorylation site of Serine 91 (E-P-S(p)-P-F) derived from Human BAD or Serine 128 (E-P-S(p)-P-F) derived from Mouse BAD.
- Isotyp
- IgG
- Top Product
- Discover our top product BAD Primärantikörper
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- Applikationshinweise
- WB:1:500-1:1000, IHC:1:50-1:100,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- BAD (BCL2-Associated Agonist of Cell Death (BAD))
- Andere Bezeichnung
- BAD (BAD Produkte)
- Synonyme
- bad antikoerper, fa01b12 antikoerper, wu:fa01b12 antikoerper, wu:fa96d04 antikoerper, BAD antikoerper, BBC2 antikoerper, BCL2L8 antikoerper, AI325008 antikoerper, Bbc2 antikoerper, BCL2-associated agonist of cell death b antikoerper, BCL2 associated agonist of cell death antikoerper, BCL2-associated agonist of cell death antikoerper, badb antikoerper, BAD antikoerper, Bad antikoerper
- Hintergrund
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Background:
The protein encoded by BAD gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Wang H.-G., Cell 87:629-638(1996).
Ottilie S., J. Biol. Chem. 272:30866-30872(1997).
The MGC Project Team, Genome Res. 14:2121-2127(2004).Aliases: AI325008 antibody, BAD antibody, BAD_HUMAN antibody, BBC 2 antibody, BBC2 antibody, BBC6 antibody, Bcl 2 Antagonist of Cell Death antibody, Bcl 2 Binding Component 6 antibody, BCL X / BCL 2 Binding Protein antibody, BCL X Binding Protein antibody, Bcl XL/Bcl 2 Associated Death Promoter antibody, Bcl-2-binding component 6 antibody, Bcl-2-like protein 8 antibody, Bcl-XL/Bcl-2-associated death promoter antibody, Bcl2 antagonist of cell death antibody, BCL2 antagonist of cell death protein antibody, BCL2 associated agonist of cell death antibody, Bcl2 Associated Death Promoter antibody, BCL2 binding component 6 antibody, BCL2 binding protein antibody, Bcl2 Like 8 Protein antibody, Bcl2-L-8 antibody, BCL2L8 antibody, Proapoptotic BH3 Only Protein antibody
- UniProt
- Q92934
- Pathways
- MAPK Signalweg, PI3K-Akt Signalweg, RTK Signalweg, Apoptose, Fc-epsilon Rezeptor Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
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