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AIRE Antikörper (pSer156)

AIRE Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7138747
  • Target Alle AIRE Antikörper anzeigen
    AIRE (Autoimmune Regulator (AIRE))
    Bindungsspezifität
    • 10
    • 8
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer156
    Reaktivität
    • 52
    • 23
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    Human
    Wirt
    • 47
    • 7
    • 1
    Kaninchen
    Klonalität
    • 54
    Polyklonal
    Konjugat
    • 39
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser AIRE Antikörper ist unkonjugiert
    Applikation
    • 40
    • 25
    • 19
    • 8
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    Immunogen
    Peptide sequence around phosphorylation site of Serine156 P-G-S(p)-Q-L) derived from Human AIRE.
    Isotyp
    IgG
    Top Product
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  • Applikationshinweise
    WB:1:500-1:1000,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    AIRE (Autoimmune Regulator (AIRE))
    Andere Bezeichnung
    AIRE (AIRE Produkte)
    Synonyme
    AIRE1 antikoerper, APECED antikoerper, APS1 antikoerper, APSI antikoerper, PGA1 antikoerper, autoimmune regulator antikoerper, autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) antikoerper, AaeL_AAEL013794 antikoerper, CpipJ_CPIJ001208 antikoerper, CpipJ_CPIJ001209 antikoerper, AIRE antikoerper, Aire antikoerper
    Hintergrund

    Background:

    The function of the protein encoded by this gene is not well defined, however it contains zinc finger motifs suggestive of a transcription factor. The protein (isoform 1) is localized to both the nucleus and cytoplasm. Three splice variant mRNAs products have been described [1]. The longer AIRE-1 mRNA appears to be more abundant and includes exons 1 through 14. Splice variant AIRE-2 includes a portion of the non-coding region of exon 1, an alternatively spliced longer exon 8, plus exons 9 through 14. Variant AIRE-3 includes the same exon 1-8-9 sequences as found in AIRE-2 but utilizes additional alternative splicing in exon 10 that shifts the reading frame such that a stop codon in exon 12 is utilized.

    Nagamine K., Nat. Genet. 17:393-398(1997).
    Aaltonen J., Nat. Genet. 17:399-403(1997).
    Hattori M., Nature 405:311-319(2000).

    Aliases: AIRE antibody, AIRE_HUMAN antibody, AIRE1 antibody, APECED antibody, APECED protein antibody, APS1 antibody, APSI antibody, Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein antibody, Autoimmune regulator antibody, Autoimmune regulator protein antibody, PGA1 antibody

    UniProt
    O43918
    Pathways
    Chromatin Binding
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