MED1 Antikörper (pThr1457)

Produktnummer ABIN7138778

Produktdetails anti-MED1 Antikörper

Target: MED1 (Mediator Complex Subunit 1 (MED1))

Bindungsspezifität: pThr1457

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human, Maus

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of Threonine 1457(A-Y-T(p)-P-Q) derived from Human PPAR-BP.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:1000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MED1

Target: MED1 (Mediator Complex Subunit 1 (MED1))

Andere Bezeichnung: MED1 (MED1 Produkte)

Synonyme: CRSP1 antikoerper, CRSP200 antikoerper, DRIP205 antikoerper, DRIP230 antikoerper, PBP antikoerper, PPARBP antikoerper, PPARGBP antikoerper, RB18A antikoerper, TRAP220 antikoerper, TRIP2 antikoerper, CRSP-1 antikoerper, MED1 antikoerper, pbp antikoerper, nbr1 antikoerper, crsp1 antikoerper, rb18a antikoerper, trip2 antikoerper, pparbp antikoerper, crsp200 antikoerper, drip205 antikoerper, drip230 antikoerper, ppargbp antikoerper, trap220 antikoerper, CG7162 antikoerper, Dmel\\CG7162 antikoerper, Med1 antikoerper, Med1/SOP3/TRAP220 antikoerper, Trap220 antikoerper, dTRAP220 antikoerper, AI480703 antikoerper, CRSP210 antikoerper, Pparbp antikoerper, l11Jus15 antikoerper, RGD1559552 antikoerper, mediator complex subunit 1 antikoerper, calcitonin-related polypeptide beta antikoerper, Mediator complex subunit 1 antikoerper, mediator of RNA polymerase II transcription subunit 1 antikoerper, MED1 antikoerper, CALCB antikoerper, med1 antikoerper, Med1 antikoerper

Hintergrund:

Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Aliases: Activator-recruited cofactor 205 kDa component antibody, ARC205 antibody, CRSP1 antibody, CRSP200 antibody, DRIP205 antibody, DRIP230 antibody, MED1 antibody, MED1_HUMAN antibody, Mediator complex subunit 1 antibody, Mediator of RNA polymerase II transcription subunit 1 antibody, p53 regulatory protein RB18A antibody, PBP antibody, Peroxisome proliferator-activated receptor-binding protein antibody, PPAR binding protein antibody, PPAR-binding protein antibody, PPARBP antibody, PPARGBP antibody, RB18A antibody, Thyroid hormone receptor-associated protein complex 220 kDa component antibody, Thyroid receptor-interacting protein 2 antibody, TR-interacting protein 2 antibody, Trap220 antibody, TRIP-2 antibody, TRIP2 antibody, Vitamin D receptor-interacting protein complex component DRIP205 antibody

UniProt: Q15648

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha