TCF3 Antikörper (pThr355)
-
- Target Alle TCF3 Antikörper anzeigen
- TCF3 (Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3))
-
Bindungsspezifität
- pThr355
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser TCF3 Antikörper ist unkonjugiert
-
Applikation
- ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Immunogen
- Peptide sequence around phosphorylation site of threonine 355 (P-S-T(p)-P-V) derived from Human E2A .
- Isotyp
- IgG
- Top Product
- Discover our top product TCF3 Primärantikörper
-
-
- Applikationshinweise
- IHC:1:50-1:100,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Target
- TCF3 (Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3))
- Andere Bezeichnung
- TCF3 (TCF3 Produkte)
- Synonyme
- E2A antikoerper, E47 antikoerper, ITF1 antikoerper, TCF-3 antikoerper, VDIR antikoerper, bHLHb21 antikoerper, tcf3a antikoerper, zgc:113045 antikoerper, A1 antikoerper, AA408400 antikoerper, ALF2 antikoerper, AW209082 antikoerper, E12 antikoerper, E12/E47 antikoerper, ME2 antikoerper, Pan1 antikoerper, Pan2 antikoerper, Tcfe2a antikoerper, bhlhb21 antikoerper, e2a antikoerper, itf1 antikoerper, tcfe2a antikoerper, vdir antikoerper, xtcf-3 antikoerper, xtcf3 antikoerper, G12 antikoerper, TCF7L1 antikoerper, XE3 antikoerper, transcription factor 3 antikoerper, transcription factor 3b antikoerper, transcription factor 3 L homeolog antikoerper, transcription factor E2a antikoerper, TCF3 antikoerper, tcf3b antikoerper, Tcf3 antikoerper, tcf3.L antikoerper, tcfe2a antikoerper
- Hintergrund
-
Background:
E2A is a transcription factor that plays major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Heterodimers between E2A and tissue-specific basic helix-loop-helix (bHLH) Dimers bind DNA on E-box motifs: 5'- CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Deletions in E2A have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases. Two alternatively spliced human isoforms have been described.
Kamps M.P., Cell 60:547-555(1990).
Nourse J., Cell 60:535-545(1990).
Grimwood J., Nature 428:529-535(2004).Aliases: AGM8 antibody, bHLHb21 antibody, Class B basic helix-loop-helix protein 21 antibody, E12 antibody, E2A antibody, E2A immunoglobulin enhancer binding factors E12/E47 antibody, E47 antibody, Helix loop helix protein HE47 antibody, Immunoglobulin enhancer-binding factor E12/E47 antibody, Immunoglobulin transcription factor 1 antibody, ITF1 antibody, Kappa-E2-binding factor antibody, MGC129647 antibody, MGC129648 antibody, Negative vitamin D response element binding protein antibody, NOL1-TCF3 fusion antibody, TCF-3 antibody, Tcf3 antibody, TFE2_HUMAN antibody, transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) antibody, Transcription factor 3 antibody, transcription factor 3 variant 3 antibody, Transcription factor E2-alpha antibody, Transcription factor ITF-1 antibody, VDIR antibody, VDR interacting repressor antibody, vitamin D receptor-interacting repressor antibody
- UniProt
- P15923
- Pathways
- WNT Signalweg, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Production of Molecular Mediator of Immune Response
-