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H2AFX Antikörper (pSer139)

Name: H2AFX Antikörper (pSer139)
Brand: antibodies-online
SKU: ABIN7139615
Price: 350.9 EUR
Availability: InStock

H2AFX Reaktivität: Human WB, ELISA, IF, ChIP Wirt: Kaninchen Polyclonal unconjugated

Western Blot Positive WB detected in: Hela whole cell lysate, 293 whole cell lysate, K562 whole cell lysate, HepG2 whole cell lysate All lanes: H2AFX antibody at 1. (H2AFX Antikörper (pSer139))

Chromatin Immunoprecipitation Hela (4*10 6 ) were treated with Micrococcal Nuclease, sonicated, and immunoprecipitated with 5 μg anti-H2AFX (ABIN7139615) or a control normal rabbit IgG. (H2AFX Antikörper (pSer139))

IHC

Immunofluorescence staining of Hela cells with ABIN7139615 at 1:2. (H2AFX Antikörper (pSer139))

3 Abbildungen

Produktnummer ABIN7139615

Datenblatt (PDF)

Target Alle H2AFX Antikörper anzeigen

H2AFX (H2A Histone Family, Member X (H2AFX))
Bindungsspezifität
40

26

18

11

6

5

5

5

5

4

4

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer139
Reaktivität
174

90

60

26

26

20

17

12

9

3

2

2

2

2

1
Human
Wirt
147

27

2
Kaninchen
Passende Sekundärantikörper
Klonalität
126

50
Polyklonal
Konjugat
109

8

7

5

5

4

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

1

1
Dieser H2AFX Antikörper ist unkonjugiert
Applikation
134

50

46

36

33

27

22

21

16

9

7

4

4

4

2

2

2

2

2

1

1

1

1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP)

Kreuzreaktivität

Human

Aufreinigung

Antigen Affinity Purified

Immunogen

Peptide sequence around site of Phospho-Ser (139) derived from Human Histone H2AX

Isotyp

IgG

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anti-H2A Histone Family, Member X (H2AFX) (pSer139) antibody
H2AFX Reaktivität: Human, Maus WB, BI Wirt: Maus Monoclonal N1-431 unconjugated

anti-H2A Histone Family, Member X (H2AFX) (pSer140) antibody
H2AFX Reaktivität: Human WB, ELISA, IHC (p), ICC, FACS, IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-H2A Histone Family, Member X (H2AFX) (ubLys119) antibody
H2AFX Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), ICC, IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-H2A Histone Family, Member X (H2AFX) (pSer139) antibody
H2AFX Reaktivität: Human WB, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated

anti-H2A Histone Family, Member X (H2AFX) (AA 1-30), (N-Term) antibody
H2AFX Reaktivität: Human WB, IHC (p) Wirt: Maus Monoclonal 980CT1-5-5 unconjugated

anti-H2A Histone Family, Member X (H2AFX) antibody
H2AFX Reaktivität: Human WB, IHC (p) Wirt: Maus Monoclonal 8C5 unconjugated

anti-H2A Histone Family, Member X (H2AFX) (pSer139) antibody
H2AFX Reaktivität: Human WB, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-H2A Histone Family, Member X (H2AFX) (C-Term) antibody
H2AFX Reaktivität: Human WB, IF, ICC, ChIP Wirt: Kaninchen Polyclonal unconjugated

anti-H2A Histone Family, Member X (H2AFX) (AA 12-141) antibody
H2AFX Reaktivität: Human IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Recommended dilution: WB:1:50-1:500, IF:1:1-1:10,

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C,-80 °C

Informationen zur Lagerung

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target

H2AFX (H2A Histone Family, Member X (H2AFX))

Andere Bezeichnung

H2AFX (H2AFX Produkte)

Synonyme

H2A.X antikoerper, H2A/X antikoerper, H2AX antikoerper, AW228881 antikoerper, H2ax antikoerper, Hist5-2ax antikoerper, gammaH2ax antikoerper, zgc:56329 antikoerper, h2a.x antikoerper, h2a/x antikoerper, h2ax antikoerper, RGD1566119 antikoerper, h2a antikoerper, h2afx antikoerper, H2A histone family member X antikoerper, H2A histone family, member X antikoerper, H2A histone family member X L homeolog antikoerper, histone cluster 1, H2ah antikoerper, histone cluster 2, H2ab S homeolog antikoerper, histone H2AX antikoerper, H2AFX antikoerper, H2afx antikoerper, h2afx antikoerper, h2afx.L antikoerper, HIST1H2AH antikoerper, hist2h2ab.S antikoerper, LOC100522201 antikoerper, LOC100720536 antikoerper

Hintergrund

Background: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
Aliases: H2A histone family member X antibody, H2A histone family member X antibody, H2A.FX antibody, H2A.X antibody, H2a/x antibody, H2AFX antibody, H2AX antibody, H2AX_HUMAN antibody, Histone H2A.X antibody

UniProt

P16104

Pathways

Telomere Maintenance, DNA Reparatur, Positive Regulation of Response to DNA Damage Stimulus