AMOTL2 Antikörper (AA 718-737) (Biotin)

Produktnummer ABIN7139726

Produktdetails anti-AMOTL2 Antikörper (Biotin)

Target: AMOTL2 (Angiomotin Like 2 (AMOTL2))

Bindungsspezifität: AA 718-737

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AMOTL2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Peptide sequence from Human Angiomotin-like protein 2 protein (718-737AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu AMOTL2

Target: AMOTL2 (Angiomotin Like 2 (AMOTL2))

Andere Bezeichnung: AMOTL2 (AMOTL2 Produkte)

Synonyme: LCCP antikoerper, AW549739 antikoerper, C79691 antikoerper, Lccp antikoerper, MASCOT antikoerper, mKIAA0989 antikoerper, zgc:154007 antikoerper, angiomotin like 2 antikoerper, angiomotin-like 2 antikoerper, angiomotin like 2b antikoerper, AMOTL2 antikoerper, Amotl2 antikoerper, amotl2 antikoerper, amotl2b antikoerper

Hintergrund:

Background: Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC.

Aliases: AMOL2_HUMAN antibody, Amotl2 antibody, angiomotin like 2 antibody, Angiomotin-like protein 2 antibody, KIAA0989 antibody, LCCP antibody, Leman coiled coil protein antibody, Leman coiled-coil protein antibody

UniProt: Q9Y2J4