APH1B Antikörper (AA 93-110) (FITC)
Kurzübersicht für APH1B Antikörper (AA 93-110) (FITC) (ABIN7139849)
Target
Alle APH1B (Aph1b) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 93-110
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Peptide sequence from Human Gamma-secretase subunit APH-1B protein (93-110AA)
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Isotyp
- IgG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))
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Andere Bezeichnung
- APH1B
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Hintergrund
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Background: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. Probably present in a minority of gamma-secretase complexes compared to APH1A.
Aliases: Anterior pharynx defective 1 homolog B (C. elegans) antibody, Anterior pharynx defective 1 homolog B antibody, Anterior pharynx defective 1B like antibody, Anterior pharynx defective 1b short splicing variant antibody, APH 1B antibody, Aph 1beta antibody, APH-1b antibody, Aph-1beta antibody, Aph1 beta antibody, aph1b antibody, APH1B_HUMAN antibody, Aph1beta antibody, DKFZp564D0372 antibody, Gamma secretase subunit APH 1B antibody, Gamma secretase subunit APH1B antibody, Gamma secretase sununit antibody, Gamma-secretase subunit Aph-1b antibody, Presenilin stabilisation factor like antibody, Presenilin-stabilization factor-like antibody, PRO 1328 antibody, PRO1328 antibody, PSFL antibody, TAAV 688 antibody, TAAV688 antibody
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UniProt
- Q8WW43
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Pathways
- Notch Signalweg, Neurotrophin Signalübertragung
Target
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