IgG3 Antikörper (AA 312-324)

Produktnummer ABIN7139883

Produktdetails anti-IgG3 Antikörper

Target: IgG3

Bindungsspezifität: AA 312-324

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IgG3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Peptide sequence from Human Immunoglobulin heavy constant gamma 3 protein (312-324AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu IgG3

Target: IgG3

Andere Bezeichnung: IGHG3 (IgG3 Produkte)

Synonyme: IgG3 antikoerper, Immunoglobulin heavy constant gamma 3 antikoerper, immunoglobulin heavy constant gamma 3 (G3m marker) antikoerper, Ighg3 antikoerper, IGHG3 antikoerper

Substanzklasse: Antibody

Hintergrund:

Background: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).

Aliases: IGHG3Immunoglobulin heavy constant gamma 3 antibody, HDC antibody, Heavy chain disease protein antibody, Ig gamma-3 chain C region antibody

UniProt: P01860