OPRK1 Antikörper (AA 31-50)

Produktnummer ABIN7139899

Produktdetails anti-OPRK1 Antikörper

Target: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Bindungsspezifität: AA 31-50

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OPRK1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Peptide sequence from Human Kappa-type opioid receptor protein (31-50AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu OPRK1

Target: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Andere Bezeichnung: OPRK1 (OPRK1 Produkte)

Synonyme: OPRK1 antikoerper, LOC780448 antikoerper, kor antikoerper, KOR antikoerper, OPRK antikoerper, K-OR-1 antikoerper, KOR-1 antikoerper, MSL-1 antikoerper, Oprk2 antikoerper, R21 antikoerper, opioid receptor, kappa 1 antikoerper, opioid receptor kappa 1 antikoerper, oprk1 antikoerper, OPRK1 antikoerper, Oprk1 antikoerper

Hintergrund:

Background: G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.

Aliases: K-OR-1 antibody, Kappa opioid receptor antibody, Kappa type opioid receptor antibody, Kappa-type opioid receptor antibody, KOR 1 antibody, KOR antibody, KOR-1 antibody, Opiate receptor kappa 1 antibody, Opiate receptor, kappa 1 antibody, Opioid receptor, kappa 1 antibody, OPRK 1 antibody, OPRK antibody, OPRK_HUMAN antibody, OPRK1 antibody, Oprk2 antibody, R21 antibody

UniProt: P41145