LRP1 Antikörper (AA 3924-3942)

Produktnummer ABIN7140070

Produktdetails anti-LRP1 Antikörper

Target: LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

Bindungsspezifität: AA 3924-3942

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRP1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Peptide sequence from Human Prolow-density lipoprotein receptor-related protein 1 protein (3924-3942AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu LRP1

Target: LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

Andere Bezeichnung: LRP1 (LRP1 Produkte)

Synonyme: A2MR antikoerper, APOER antikoerper, APR antikoerper, CD91 antikoerper, IGFBP3R antikoerper, LRP antikoerper, LRP1A antikoerper, TGFBR5 antikoerper, A2mr antikoerper, AI316852 antikoerper, Lrp antikoerper, LRP-1 antikoerper, LDL receptor related protein 1 antikoerper, prolow-density lipoprotein receptor-related protein 1 antikoerper, low density lipoprotein receptor-related protein 1 antikoerper, LRP1 antikoerper, Lrp1 antikoerper, LOC100414789 antikoerper

Hintergrund:

Background: Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission (PubMed:11907044, PubMed:12888553, PubMed:12713657). Acts as an alpha-2-macroglobulin receptor (PubMed:26142438).

Aliases: A2MR antibody, Alpha 2 macroglobulin receptor antibody, alpha 2MR antibody, Alpha-2-macroglobulin receptor antibody, APOER antibody, Apolipoprotein E receptor antibody, APR antibody, CD 91 antibody, CD91 antibody, CD91 antigen antibody, IGFBP3R antibody, LDL receptor related protein 1 antibody, Low density lipoprotein receptor related protein 1 antibody, Low density lipoprotein related protein 1 antibody, Low-density lipoprotein receptor-related protein 1 intracellular domain antibody, LRP 1 antibody, LRP 515 antibody, LRP 85 antibody, LRP antibody, LRP ICD antibody, LRP-1 antibody, LRP-515 antibody, LRP-85 antibody, Lrp1 antibody, LRP1 protein antibody, LRP1_HUMAN antibody, LRP1A antibody, LRP515 antibody, LRP85 antibody, LRPICD antibody, MGC88725 antibody, Prolow density lipoprotein receptor related protein 1 antibody, TbetaR V/LRP 1/IGFBP 3 receptor antibody, TbetaRV/LRP1/IGFBP3 receptor antibody, TGFBR 5 antibody, TGFBR5 antibody, Type V tgf beta receptor antibody

UniProt: Q07954

Pathways: Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling