VPS36 Antikörper (AA 87-105) (Biotin)

Produktnummer ABIN7140212

Produktdetails anti-VPS36 Antikörper (Biotin)

Target: VPS36 (Vacuolar Protein Sorting 36 (VPS36))

Bindungsspezifität: AA 87-105

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VPS36 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Peptide sequence from Human Vacuolar protein-sorting-associated protein 36 protein (87-105AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu VPS36

Target: VPS36 (Vacuolar Protein Sorting 36 (VPS36))

Andere Bezeichnung: VPS36 (VPS36 Produkte)

Hintergrund:

Background: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. Binds phosphoinosides such as PtdIns(3,4,5)P3.

Aliases: C13orf9 antibody, CGI 145 antibody, EAP45 antibody, ELL associated protein of 45 kDa antibody, ELL-associated protein of 45 kDa antibody, ESCRT-II complex subunit VPS36 antibody, Vacuolar protein sorting associated protein 36 antibody, Vacuolar protein-sorting-associated protein 36 antibody, Vps36 antibody, VPS36_HUMAN antibody

UniProt: Q86VN1