WDR77 Antikörper
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- Target Alle WDR77 Antikörper anzeigen
- WDR77 (WD Repeat Domain 77 (WDR77))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser WDR77 Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB), Immunocytochemistry (ICC)
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Affinity purified
- Immunogen
- Purified recombinant human WDR77 protein fragments expressed in E.coli.
- Isotyp
- IgG1, IgG1 kappa
- Top Product
- Discover our top product WDR77 Primärantikörper
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- Applikationshinweise
- Recommended dilution:WB:1:500-1:5000,ICC:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified mouse monoclonal in PBS( pH 7.4) containing with 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- WDR77 (WD Repeat Domain 77 (WDR77))
- Andere Bezeichnung
- WDR77 (WDR77 Produkte)
- Hintergrund
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Background: Non-catalytic component of the 20S PRMT5-containing methyltransferase complex,which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones.This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles.Might play a role in transcription regulation.The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4),methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.
Aliases: 2610312E17Rik, Androgen receptor cofactor p44, C79984, HKMT1069, MEP 50, MEP-50, MEP50, MEP50_HUMAN, Methylosome protein 50, MGC2722, Nbla10071, p44, p44/Mep50, RGD1310479, RP11 552M11.3, WD repeat containing protein 77, WD repeat domain 77,
- UniProt
- Q9BQA1
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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