WDR77 Antikörper

Produktnummer ABIN7140359

Produktdetails anti-WDR77 Antikörper

Target: WDR77 (WD Repeat Domain 77 (WDR77))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser WDR77 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunocytochemistry (ICC)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Affinity purified

Immunogen: Purified recombinant human WDR77 protein fragments expressed in E.coli.

Isotyp: IgG1, IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Recommended dilution:WB:1:500-1:5000,ICC:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified mouse monoclonal in PBS( pH 7.4) containing with 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu WDR77

Target: WDR77 (WD Repeat Domain 77 (WDR77))

Andere Bezeichnung: WDR77 (WDR77 Produkte)

Synonyme: MEP-50 antikoerper, MEP50 antikoerper, Nbla10071 antikoerper, RP11-552M11.3 antikoerper, p44 antikoerper, p44/Mep50 antikoerper, 2610003I18Rik antikoerper, 2610312E17Rik antikoerper, C79984 antikoerper, p44/MEP50 antikoerper, RGD1310479 antikoerper, mep50 antikoerper, valois antikoerper, WDR77 antikoerper, zgc:65780 antikoerper, zgc:77274 antikoerper, WD repeat domain 77 antikoerper, WD repeat domain 77 S homeolog antikoerper, WDR77 antikoerper, Wdr77 antikoerper, wdr77.S antikoerper, wdr77 antikoerper

Hintergrund:

Background: Non-catalytic component of the 20S PRMT5-containing methyltransferase complex,which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones.This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles.Might play a role in transcription regulation.The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4),methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.

Aliases: 2610312E17Rik, Androgen receptor cofactor p44, C79984, HKMT1069, MEP 50, MEP-50, MEP50, MEP50_HUMAN, Methylosome protein 50, MGC2722, Nbla10071, p44, p44/Mep50, RGD1310479, RP11 552M11.3, WD repeat containing protein 77, WD repeat domain 77,

UniProt: Q9BQA1

Pathways: Ribonucleoprotein Complex Subunit Organization