IFNK Antikörper (AA 24-195) (Biotin)

Produktnummer ABIN7140831

Produktdetails anti-IFNK Antikörper (Biotin)

Target: IFNK (Interferon, kappa (IFNK))

Bindungsspezifität: AA 24-195

Reaktivität: Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IFNK Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Rind (Kuh)

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Bovine Interferon tau-1 protein (24-195AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu IFNK

Target: IFNK (Interferon, kappa (IFNK))

Andere Bezeichnung: IFNT1 (IFNK Produkte)

Synonyme: IFNK antikoerper, IFNT1 antikoerper, INFE1 antikoerper, RP11-27J8.1 antikoerper, interferon kappa antikoerper, IFNK antikoerper, Ifnk antikoerper

Hintergrund:

Background: Paracrine hormone primarily responsible for maternal recognition of pregnancy. Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium. This results in the suppression of the pulsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity. This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stimulates the secretion by the endometrium of the nutrients required for the growth of the conceptus. In summary, displays particularly high antiviral and antiproliferative potency concurrently with particular weak cytotoxicity, high antiluteolytic activity and immunomodulatory properties. In contrast with other IFNs, IFN-tau is not virally inducible.

Aliases: IFNT1 antibody, Interferon tau-1 antibody, IFN-tau-1 antibody, Antiluteolysin antibody, Trophoblast antiluteolytic protein antibody, Trophoblast protein 1 antibody, TP-1 antibody, Trophoblastin antibody

UniProt: P15696