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CD14 Antikörper

CD14 Reaktivität: Human IHC, ELISA Wirt: Maus Monoclonal 1A3B6 unconjugated
Produktnummer ABIN7140933
  • Target Alle CD14 Antikörper anzeigen
    CD14
    Reaktivität
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    Human
    Wirt
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    Maus
    Klonalität
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    • 54
    Monoklonal
    Konjugat
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    Dieser CD14 Antikörper ist unkonjugiert
    Applikation
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    Immunohistochemistry (IHC), ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    Protein G purified
    Immunogen
    Recombinant CD14 Protein
    Klon
    1A3B6
    Isotyp
    IgG2b
    Top Product
    Discover our top product CD14 Primärantikörper
  • Applikationshinweise
    Recommended dilution:IHC:1:50-1:500,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    CD14
    Andere Bezeichnung
    CD14 (CD14 Produkte)
    Synonyme
    CD14 molecule antikoerper, CD14 antigen antikoerper, CD14 antikoerper, Cd14 antikoerper
    Hintergrund

    Background: As a component of the innate immune system, the cell surface glycoprotein CD14 is a myelomonocytic differentiation antigen preferentially expressed on monocytes, macrophages, and activated granulocytes. CD14 exists as two forms, either anchored into the membrane by a GPI-anchor tail (mCD14) or present as a soluble form (sCD14) in normal serum and body fluids. CD14 was first described as a pattern recognition receptor for lipopolysaccharide (LPS) and a variety of ligands derived from different microbial sources, along with the co-receptors Toll-like receptor TLR 4 and MD-2. The binding of CD14 and LPS depends on the presence and catalytic activity of lipopolysaccharide-binding protein (LBP). Besides its endotoxin signaling function, CD14 has been proposed to be involved in various biological processes, including transportation of other lipids, cell-cell interaction during different immune responses, as well as recognition of apoptotic cells. Multiple transcript variants resulting from alternative splicing encode the same isoform of CD14.

    Aliases: CD14, CD14 Molecule

    UniProt
    P08571
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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