MICAL1 Antikörper (AA 806-1067) (Biotin)
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- Target Alle MICAL1 Antikörper anzeigen
- MICAL1 (Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 1 (MICAL1))
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Bindungsspezifität
- AA 806-1067
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MICAL1 Antikörper ist konjugiert mit Biotin
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Applikation
- ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human [F-actin]-methionine sulfoxide oxidase MICAL1 protein (806-1067AA)
- Isotyp
- IgG
- Top Product
- Discover our top product MICAL1 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- MICAL1 (Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 1 (MICAL1))
- Andere Bezeichnung
- MICAL1 (MICAL1 Produkte)
- Synonyme
- MICAL antikoerper, MICAL-1 antikoerper, NICAL antikoerper, Nical antikoerper, zgc:171928 antikoerper, microtubule associated monooxygenase, calponin and LIM domain containing 1 antikoerper, MICAL1 antikoerper, Mical1 antikoerper, mical1 antikoerper
- Hintergrund
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Background: Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Acts by modifying actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization (Probable). Acts as a cytoskeletal regulator that connects NEDD9 to intermediate filaments. Also acts as a negative regulator of apoptosis via its interaction with STK38 and STK38L, acts by antagonizing STK38 and STK38L activation by MST1/STK4. Involved in regulation of lamina-specific connectivity in the nervous system such as the development of lamina-restricted hippocampal connections. Through redox regulation of the actin cytoskeleton controls the intracellular distribution of sectrory vesicles containing L1/neurofascin/NgCAM family proteins in neurons, thereby regulating their cell surface levels (By similarity). May act as Rab effector protein and play a role in vesicle trafficking.
Aliases: CasL interacting molecule antibody, DKFZp434B1517 antibody, FLJ11937 antibody, FLJ21739 antibody, MICA1_HUMAN antibody, MICAL 1 antibody, MICAL antibody, MICAL1 antibody, microtubule associated monoxygenase, calponin and LIM domain containing 1 antibody, Molecule interacting with CasL protein 1 antibody, NEDD9 interacting protein with calponin homology and LIM domains antibody, NEDD9-interacting protein with calponin homology and LIM domains antibody, NICAL antibody, OTTHUMP00000016969 antibody
- UniProt
- Q8TDZ2
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