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PDK3 Antikörper (AA 137-406)

PDK3 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7142007
  • Target Alle PDK3 Antikörper anzeigen
    PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
    Bindungsspezifität
    • 9
    • 9
    • 9
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 137-406
    Reaktivität
    • 31
    • 30
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 49
    • 3
    Kaninchen
    Klonalität
    • 49
    • 3
    Polyklonal
    Konjugat
    • 29
    • 6
    • 5
    • 4
    • 4
    • 4
    Dieser PDK3 Antikörper ist unkonjugiert
    Applikation
    • 45
    • 34
    • 20
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human, Maus
    Aufreinigung
    Antigen Affinity Purified
    Immunogen
    Recombinant Human [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial protein (137-406AA)
    Isotyp
    IgG
    Top Product
    Discover our top product PDK3 Primärantikörper
  • Applikationshinweise
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
    Andere Bezeichnung
    PDK3 (PDK3 Produkte)
    Synonyme
    pdk3 antikoerper, PDK3 antikoerper, 2610001M10Rik antikoerper, AI035637 antikoerper, zgc:158702 antikoerper, pyruvate dehydrogenase kinase 3 antikoerper, pyruvate dehydrogenase kinase, isozyme 3a antikoerper, pyruvate dehydrogenase kinase, isoenzyme 3 antikoerper, fragile site, 5-azacytidine type, common, fra(1)(q12) antikoerper, pyruvate dehydrogenase kinase, isozyme 3b antikoerper, PDK3 antikoerper, Pdk3 antikoerper, pdk3a antikoerper, pdk3 antikoerper, FRA1J antikoerper, pdk3b antikoerper
    Hintergrund

    Background: Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and increases fat metabolism in response to prolonged fasting, and as adaptation to a high-fat diet. Plays a role in glucose homeostasis and in maintaining normal blood glucose levels in function of nutrient levels and under starvation. Plays a role in the generation of reactive oxygen species.

    Aliases: [Pyruvate dehydrogenase [lipoamide] kinase isozyme 3 mitochondrial antibody, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3 antibody, CMTX6 antibody, GS1-358P8.4 antibody, mitochondrial antibody, PDK3 antibody, PDK3_HUMAN antibody, Pyruvate dehydrogenase kinase isoenzyme 3 antibody, Pyruvate dehydrogenase kinase isoform 3 antibody, Pyruvate dehydrogenase kinase isozyme 3 antibody, Pyruvate dehydrogenase lipoamide kinase isozyme 3 mitochondrial antibody

    UniProt
    Q15120
    Pathways
    PI3K-Akt Signalweg, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effekt
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