PLCD4 Antikörper (AA 1-290)

Produktnummer ABIN7142053

Produktdetails anti-PLCD4 Antikörper

Target: PLCD4 (Phospholipase C, delta 4 (PLCD4))

Bindungsspezifität: AA 1-290

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLCD4 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 protein (1-290AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PLCD4

Target: PLCD4 (Phospholipase C, delta 4 (PLCD4))

Andere Bezeichnung: PLCD4 (PLCD4 Produkte)

Synonyme: PLCD4 antikoerper, PLCL3 antikoerper, si:dkeyp-84a8.7 antikoerper, 4921507K24Rik antikoerper, phospholipase C eta 1 antikoerper, phospholipase C delta 4 antikoerper, phospholipase C, delta 4a antikoerper, phospholipase C, delta 4 antikoerper, phospholipase C delta 4 L homeolog antikoerper, PLCH1 antikoerper, PLCD4 antikoerper, plcd4a antikoerper, plcd4 antikoerper, Plcd4 antikoerper, plcd4.L antikoerper

Hintergrund:

Background: Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation.

Aliases: 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase delta 4 antibody, 1-phosphatidylinositol 4 antibody, 1-phosphatidylinositol-4 antibody, 5-bisphosphate phosphodiesterase delta-4 antibody, hPLCD4 antibody, MGC12837 antibody, Phosphoinositide phospholipase C delta 4 antibody, Phosphoinositide phospholipase C-delta-4 antibody, Phospholipase C delta 4 antibody, Phospholipase C-delta-4 antibody, PLC delta 4 antibody, PLC delta4 antibody, PLC-delta-4 antibody, PLCD4 antibody, PLCD4_HUMAN antibody

UniProt: Q9BRC7

Pathways: Inositol Metabolic Process