PRKAG3 Antikörper (AA 1-210)
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- Target Alle PRKAG3 Antikörper anzeigen
- PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))
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Bindungsspezifität
- AA 1-210
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PRKAG3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- Antigen Affinity Purified
- Immunogen
- Recombinant Human 5\\\'-AMP-activated protein kinase subunit gamma-3 protein (1-210AA)
- Isotyp
- IgG
- Top Product
- Discover our top product PRKAG3 Primärantikörper
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- Applikationshinweise
- Recommended dilution: WB:1:500-1:2000,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))
- Andere Bezeichnung
- PRKAG3 (PRKAG3 Produkte)
- Synonyme
- Ampkg3 antikoerper, prkag3-a antikoerper, PRKAG3 antikoerper, AMPKG3 antikoerper, AMPKg3L antikoerper, AMPKg3S antikoerper, Amkg3 antikoerper, protein kinase AMP-activated non-catalytic subunit gamma 3 antikoerper, protein kinase, AMP-activated, gamma 3 non-catalytic subunit S homeolog antikoerper, protein kinase, AMP-activated, gamma 3 non-catatlytic subunit b antikoerper, protein kinase, AMP-activated, gamma 3 non-catatlytic subunit antikoerper, Prkag3 antikoerper, PRKAG3 antikoerper, prkag3.S antikoerper, prkag3-b antikoerper
- Hintergrund
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Background: AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton, probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.
Aliases: 5 AMP activated protein kinase subunit gamma 3 antibody, 5''-AMP-activated protein kinase subunit gamma-3 antibody, AAKG3_HUMAN antibody, AMPK gamma 3 chain antibody, AMPK gamma3 antibody, AMPK subunit gamma-3 antibody, AMPKG3 antibody, PRKAG3 antibody, Protein kinase AMP activated gamma 3 non catalytic subunit antibody
- UniProt
- Q9UGI9
- Pathways
- AMPK Signaling, Cellular Glucan Metabolic Process, Warburg Effekt
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