Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

RPL13A Antikörper (AA 63-190)

RPL13A Reaktivität: Human ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7142744
  • Target Alle RPL13A Antikörper anzeigen
    RPL13A (Ribosomal Protein L13a (RPL13A))
    Bindungsspezifität
    • 11
    • 4
    • 4
    • 1
    • 1
    • 1
    AA 63-190
    Reaktivität
    • 14
    • 9
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 20
    Kaninchen
    Klonalität
    • 20
    Polyklonal
    Konjugat
    • 9
    • 3
    • 2
    • 2
    • 2
    • 2
    Dieser RPL13A Antikörper ist unkonjugiert
    Applikation
    • 16
    • 13
    • 2
    • 2
    • 2
    • 1
    ELISA, Immunofluorescence (IF)
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human 60S ribosomal protein L13a protein (63-190AA)
    Isotyp
    IgG
    Top Product
    Discover our top product RPL13A Primärantikörper
  • Applikationshinweise
    Recommended dilution: IF:1:50-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    RPL13A (Ribosomal Protein L13a (RPL13A))
    Andere Bezeichnung
    RPL13A (RPL13A Produkte)
    Hintergrund

    Background: Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3\'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex. Involved in methylation of rRNA.

    Aliases: RPL13A antibody, 60S ribosomal protein L13a antibody, 23 kDa highly basic protein antibody, Large ribosomal subunit protein uL13 antibody

    UniProt
    P40429
Sie sind hier:
Kundenservice