MMP2 Antikörper (AA 445-660)

Produktnummer ABIN7142866

Produktdetails anti-MMP2 Antikörper

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Bindungsspezifität: AA 445-660

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human 72 kDa type IV collagenase protein (445-660AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MMP2

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Andere Bezeichnung: MMP2 (MMP2 Produkte)

Hintergrund:

Background: Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14.

Aliases: 72 kDa gelatinase antibody, 72kD type IV collagenase antibody, CLG 4 antibody, CLG 4A antibody, CLG4 antibody, CLG4A antibody, Collagenase Type 4 alpha antibody, Collagenase type IV A antibody, Gelatinase A antibody, Gelatinase alpha antibody, Gelatinase neutrophil antibody, Matrix metallopeptidase 2 gelatinase A 72 kDa gelatinase 72 kDa type IV collagenase antibody, Matrix metalloproteinase 2 (gelatinase A, 72 kDa gelatinase, 72 kDa type IV collagenase) antibody, Matrix Metalloproteinase 2 antibody, Matrix metalloproteinase II antibody, Matrix metalloproteinase-2 antibody, MMP 2 antibody, MMP II antibody, MMP-2 antibody, MMP2 antibody, MMP2_HUMAN antibody, MONA antibody, Neutrophil gelatinase antibody, PEX antibody, TBE 1 antibody, TBE-1 antibody

UniProt: P08253

Pathways: Activation of Innate immune Response