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MOCS3 Antikörper (AA 271-460)

MOCS3 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7143362
  • Target Alle MOCS3 Antikörper anzeigen
    MOCS3 (Molybdenum Cofactor Synthesis 3 (MOCS3))
    Bindungsspezifität
    • 14
    • 7
    • 6
    • 4
    • 1
    AA 271-460
    Reaktivität
    • 19
    • 17
    • 2
    Human
    Wirt
    • 26
    • 5
    Kaninchen
    Klonalität
    • 29
    • 2
    Polyklonal
    Konjugat
    • 18
    • 3
    • 3
    • 3
    • 2
    • 2
    Dieser MOCS3 Antikörper ist unkonjugiert
    Applikation
    • 27
    • 18
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Adenylyltransferase and sulfurtransferase MOCS3 protein (271-460AA)
    Isotyp
    IgG
  • Applikationshinweise
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    MOCS3 (Molybdenum Cofactor Synthesis 3 (MOCS3))
    Andere Bezeichnung
    MOCS3 (MOCS3 Produkte)
    Synonyme
    MOCS3 antikoerper, DDBDRAFT_0189692 antikoerper, DDBDRAFT_0267172 antikoerper, DDB_0189692 antikoerper, DDB_0267172 antikoerper, UBA4 antikoerper, 1700020H17Rik antikoerper, Uba4 antikoerper, zgc:55696 antikoerper, uba4 antikoerper, molybdenum cofactor synthesis 3 antikoerper, molybdenum cofactor synthesis 3 L homeolog antikoerper, MOCS3 antikoerper, mocs3 antikoerper, Mocs3 antikoerper, mocs3.L antikoerper
    Hintergrund

    Background: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor, NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.

    Aliases: Adenylyltransferase MOCS3 antibody, dJ914P20.3 antibody, MGC9252 antibody, MOCS 3 antibody, MOCS3 antibody, MOCS3_HUMAN antibody, Molybdenum cofactor synthesis 3 antibody, Molybdenum cofactor synthesis protein 3 antibody, Molybdopterin synthase sulfurylase antibody, Molybdopterin-synthase sulfurtransferase antibody, MPT synthase sulfurylase antibody, Sulfur carrier protein MOCS2A adenylyltransferase antibody, Sulfur carrier protein MOCS2A sulfurtransferase antibody, Sulfurtransferase MOCS3 antibody, UBA 4 antibody, UBA4 ubiquitin activating enzyme E1 homolog antibody, UBA4 antibody

    UniProt
    O95396
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