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MOCS3 Antikörper (AA 279-404)

MOCS3 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7143364
  • Target Alle MOCS3 Antikörper anzeigen
    MOCS3 (Molybdenum Cofactor Synthesis 3 (MOCS3))
    Bindungsspezifität
    • 14
    • 7
    • 6
    • 3
    • 1
    • 1
    AA 279-404
    Reaktivität
    • 19
    • 17
    • 2
    Human
    Wirt
    • 26
    • 5
    Kaninchen
    Klonalität
    • 29
    • 2
    Polyklonal
    Konjugat
    • 18
    • 3
    • 3
    • 3
    • 2
    • 2
    Dieser MOCS3 Antikörper ist unkonjugiert
    Applikation
    • 27
    • 18
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Kreuzreaktivität
    Human, Maus
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Adenylyltransferase and sulfurtransferase MOCS3 protein (279-404aa)
    Isotyp
    IgG
    Top Product
    Discover our top product MOCS3 Primärantikörper
  • Applikationshinweise
    Recommended dilution: WB:1:1000-1:5000,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    MOCS3 (Molybdenum Cofactor Synthesis 3 (MOCS3))
    Andere Bezeichnung
    MOCS3 (MOCS3 Produkte)
    Synonyme
    MOCS3 antikoerper, DDBDRAFT_0189692 antikoerper, DDBDRAFT_0267172 antikoerper, DDB_0189692 antikoerper, DDB_0267172 antikoerper, UBA4 antikoerper, 1700020H17Rik antikoerper, Uba4 antikoerper, zgc:55696 antikoerper, uba4 antikoerper, molybdenum cofactor synthesis 3 antikoerper, molybdenum cofactor synthesis 3 L homeolog antikoerper, MOCS3 antikoerper, mocs3 antikoerper, Mocs3 antikoerper, mocs3.L antikoerper
    Hintergrund

    Background: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor, NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.

    Aliases: Adenylyltransferase and sulfurtransferase MOCS3 (Molybdenum cofactor synthesis protein 3) (Molybdopterin synthase sulfurylase) (MPT synthase sulfurylase) [Includes: Molybdopterin-synthase adenylyltransferase (EC 2.7.7.80) (Adenylyltransferase MOCS3) (Sulfur carrier protein MOCS2A adenylyltransferase), Molybdopterin-synthase sulfurtransferase (EC 2.8.1.11) (Sulfur carrier protein MOCS2A sulfurtransferase) (Sulfurtransferase MOCS3)], MOCS3, UBA4

    UniProt
    O95396
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