ASIP Antikörper (AA 23-112)

Produktnummer ABIN7143597

Produktdetails anti-ASIP Antikörper

Target: ASIP (Agouti Signaling Protein (ASIP))

Bindungsspezifität: AA 23-112

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASIP Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Agouti-signaling protein (23-112AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ASIP

Target: ASIP (Agouti Signaling Protein (ASIP))

Andere Bezeichnung: ASIP (ASIP Produkte)

Synonyme: AGSW antikoerper, AGTI antikoerper, AGTIL antikoerper, ASP antikoerper, SHEP9 antikoerper, ASIP antikoerper, AA960621 antikoerper, AI256638 antikoerper, D8Ertd580e antikoerper, PAR-3 antikoerper, Par3 antikoerper, Pard3a antikoerper, agouti signaling protein antikoerper, par-3 family cell polarity regulator antikoerper, ASIP antikoerper, Asip antikoerper, asip antikoerper, Pard3 antikoerper

Hintergrund:

Background: Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). In higher primates, agouti may affect the quality of hair pigmentation rather than its pattern of deposition. Could well play a role in neuroendocrine aspects of melanocortin action. May have some functional role in regulating the lipid metabolism with adipocytes.

Aliases: ASIP antibody, AGTI antibody, AGTIL antibody, ASP antibody, Agouti-signaling protein antibody, ASP antibody, Agouti switch protein antibody

UniProt: P42127

Pathways: Cell-Cell Junction Organization, Feeding Behaviour