ALKBH1 Antikörper (AA 110-389)

Produktnummer ABIN7143716

Produktdetails anti-ALKBH1 Antikörper

Target: ALKBH1 (AlkB, Alkylation Repair Homolog 1 (ALKBH1))

Bindungsspezifität: AA 110-389

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALKBH1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Alkylated DNA repair protein alkB homolog 1 protein (110-389AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ALKBH1

Target: ALKBH1 (AlkB, Alkylation Repair Homolog 1 (ALKBH1))

Andere Bezeichnung: ALKBH1 (ALKBH1 Produkte)

Hintergrund:

Background: Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate and iron. May have a role in placental trophoblast lineage differentiation (By similarity). Has DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites. DNA lyase activity does not require alpha-ketoglutarate and iron.

Aliases: ABH antibody, ABH1 antibody, alkB antibody, alkB homolog 1 histone H2A dioxygenase antibody, AlkB, alkylation repair homolog 1 (E. coli) antibody, ALKB1_HUMAN antibody, ALKBH antibody, ALKBH1 antibody, Alkylated DNA repair protein alkB homolog 1 antibody, Alkylation repair homolog 1 antibody, Alkylation repair, alkB homolog antibody, Alpha-ketoglutarate-dependent dioxygenase ABH1 antibody, DNA lyase ABH1 antibody, DNA oxidative demethylase ALKBH1 antibody, hABH antibody

UniProt: Q13686

Pathways: DNA Reparatur