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alpha Actinin 4 Antikörper (AA 160-440)

Name: alpha Actinin 4 Antikörper (AA 160-440)
Brand: antibodies-online
SKU: ABIN7143827
Price: 328.9 EUR
Availability: InStock

ACTN4 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

Western Blot Positive WB detected in: Hela whole cell lysate, MCF-7 whole cell lysate, HepG2 whole cell lysate, 293T whole cell lysate, Rat liver tissue All lanes: ACTN4 antibody at 3. (alpha Actinin 4 Antikörper (AA 160-440))

Immunofluorescence staining of A549 cells with ABIN7143827 at 1:66, counter-stained with DAPI. (alpha Actinin 4 Antikörper (AA 160-440))

IHC image of ABIN7143827 diluted at 1:200 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. (alpha Actinin 4 Antikörper (AA 160-440))

IHC

IHC image of ABIN7143827 diluted at 1:200 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. (alpha Actinin 4 Antikörper (AA 160-440))

IHC

4 Abbildungen

Produktnummer ABIN7143827

Datenblatt (PDF)

Target Alle alpha Actinin 4 (ACTN4) Antikörper anzeigen

alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
Bindungsspezifität
10

7

6

4

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 160-440
Reaktivität
91

50

46

8

5

4

4

3

3

3

2

2

1

1

1
Human
Wirt
84

7
Kaninchen
Passende Sekundärantikörper
Klonalität
72

18
Polyklonal
Konjugat
55

6

6

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
Dieser alpha Actinin 4 Antikörper ist unkonjugiert
Applikation
68

30

25

17

16

15

13

12

8

2

2

1

1

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität

Human, Ratte

Aufreinigung

>95%, Protein G purified

Immunogen

Recombinant Human Alpha-actinin-4 protein (160-440AA)

Isotyp

IgG

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anti-Actinin, alpha 4 (ACTN4) (AA 561-661) antibody
ACTN4 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Actinin, alpha 4 (ACTN4) (C-Term) antibody
ACTN4 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200,

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C,-80 °C

Informationen zur Lagerung

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target

alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

Andere Bezeichnung

ACTN4 (ACTN4 Produkte)

Synonyme

fsgs antikoerper, fsgs1 antikoerper, C77391 antikoerper, ACTININ-4 antikoerper, FSGS antikoerper, FSGS1 antikoerper, wu:fb53f05 antikoerper, zgc:63508 antikoerper, actinin alpha 4 antikoerper, actinin, alpha 4 antikoerper, actinin alpha 4 S homeolog antikoerper, actn4 antikoerper, ACTN4 antikoerper, Actn4 antikoerper, actn4.S antikoerper

Hintergrund

Background: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (Probable). Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation (PubMed:15772161). Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions (By similarity). May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA (PubMed:22351778).
Aliases: actinin 4 antibody, Actinin alpha 4 antibody, actinin4 antibody, ACTN 4 antibody, ACTN4 antibody, ACTN4_HUMAN antibody, Alpha-actinin-4 antibody, DKFZp686K23158 antibody, F actin cross linking protein antibody, F-actin cross-linking protein antibody, Focal segmental glomerulosclerosis 1 antibody, FSGS 1 antibody, FSGS antibody, FSGS1 antibody, Non muscle alpha actinin 4 antibody, Non-muscle alpha-actinin 4 antibody

UniProt

O43707

Pathways

Proton Transport