ALKBH3 Antikörper (AA 1-286)

Produktnummer ABIN7143890

Produktdetails anti-ALKBH3 Antikörper

Target: ALKBH3 (AlkB, Alkylation Repair Homolog 3 (ALKBH3))

Bindungsspezifität: AA 1-286

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALKBH3 Antikörper ist unkonjugiert

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 protein (1-286AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ALKBH3

Target: ALKBH3 (AlkB, Alkylation Repair Homolog 3 (ALKBH3))

Andere Bezeichnung: ALKBH3 (ALKBH3 Produkte)

Synonyme: ABH3 antikoerper, DEPC-1 antikoerper, DEPC1 antikoerper, PCA1 antikoerper, 1700108H04Rik antikoerper, 1810020C19Rik antikoerper, Abh3 antikoerper, mABH3 antikoerper, alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase L homeolog antikoerper, alkB homolog 3, alpha-ketoglutaratedependent dioxygenase antikoerper, alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase antikoerper, alkbh3.L antikoerper, ALKBH3 antikoerper, Alkbh3 antikoerper

Hintergrund:

Background: Dioxygenase that repairs alkylated DNA containing 1-methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron.

Aliases: 1700108H04Rik antibody, 1810020C19Rik antibody, ABH3 antibody, AlkB homolog 3 antibody, alkB, alkylation repair homolog 3 (E. coli) antibody, ALKB3_HUMAN antibody, ALKBH3 antibody, Alkylated DNA repair protein alkB homolog 3 antibody, alkylation repair homolog 3 antibody, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 antibody, DEPC 1 antibody, DEPC-1 antibody, DEPC1 antibody, EC 1.14.11. antibody, FLJ43614 antibody, mABH3 antibody, MGC118790 antibody, MGC118792 antibody, MGC118793 antibody, MGC134125 antibody, PCA1 antibody, Prostate cancer antigen 1 antibody, Prostate cancer antigen-1 antibody, RP23-375N21.4 antibody

UniProt: Q96Q83

Pathways: DNA Reparatur